Weak/Bad batch of trt cream

Chet002

New Member
My first month using TRT cream went pretty much as expected. Increased libido, less anxiety, slight increase in skin oil production etc. Within a day or two of starting the second month’s canister, I noticed deceased libido, some increased anxiety, dryness of skin etc. Has there been issues with inconsistent creams? Suggestions on what to do? I’m about 10 days into the second canister.....
 
It could be a weaker batch or you could be past your honeymoon with TRT.

The first two weeks of testosterone can be awesome, because of the honeymoon effect. At least it was that way for me.
 
Yes, more likely your natural production is shutting down and you are feeling that effect. You will need 6-8 weeks to stabilize with the external T sources.
 
If your Topi-Click containers were purchased at the same time it would be unlikely for them to be different from a quality perspective.
 
It could be that your LH is now shut down and your body is trying to make adjustments to back fill...so you might need to add another hormone to your protocol to back-fill this void and get it back again...dhea and prog did it for me.
 
My first month using TRT cream went pretty much as expected. Increased libido, less anxiety, slight increase in skin oil production etc. Within a day or two of starting the second month’s canister, I noticed deceased libido, some increased anxiety, dryness of skin etc. Has there been issues with inconsistent creams? Suggestions on what to do? I’m about 10 days into the second canister.....
One of my main complaints about compounded cream is that pharmacies are not required to submit 3rd party testing of non injectable meds. Switch to Medquest Pharmacy our of Salt Lake City, Utah if you can as they have every batch tested by a 3rd party
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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