Update on Kyzatrex/T cyp hybrid protocol

ignition

New Member
Super brief history: TRT 8 years, previously Topical then 7 years injections, T cyp. Eventually moved to to Cataceous' Enanthate/Prop blend, with a bit higher ratio of prop. Ended up doing really well at 7mg/daily.

Except HCT. Had to get off the phlebotomy train.

Was a real challenge to find a good provider for Kyzatrex, took many months.

Started on 200mg 2/day, was way too high and over stimulated. Felt like Adrenals were stressed, spiking/crashing daily. Peak levels were supra physiological with Free T at 39

Reduced to 100mg 2/day. better, but on the side of too little and daily cyclical fatigue. Got labs at trough:
-Testosterone, Total, LC/MS 135.4ng/dL 264.0-916.0 Low
-Testosterone, Free 4.93, 5.00-21.00

Tried 3x a day, kept me awake at night.

So added 5mg T cyp E3D then labs, then bumped to 6mg then labs (below), now bumping to 7mg T cyp E3D with 100mg Kyzatrex 2/day. Doing quite well. Nothing symptomatic to complain about. Just bumping the injection dose to keep the daily trough out of the basement.

Current numbers, Testosterone, F Eqlib+T LC/MS:

Peak:
-Testosterone, Total, LC/MS 756.2 264.0-916.0
-Testosterone, Free 24.43 High 5.00-21.00

Trough:
-Testosterone, Total, 212.0 LC/MS A, Low
-Testosterone, Free 5.7, 5.00-21.00

HCT 49%
HGB 17.6 g/dl
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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