Seems these dosage recommendation of max of around 1mg make sense. I think too much of it pushes the brain in a hangover suppressed state into the following day which then somehow triggers a cascade of the depressive symptoms, a pattern which we have previously experienced.Experienced this over a range between 1.5 to 6 mg and the negative effects were more intense at higher doses.
For me, pregnenolone (50mg oral) before bed knocked me out the following day. I'm a night owl and melatonin (1.2mg) helps me to fall asleep earlier.
On an upper personal range of testo, I think pregnenolone is balancing out the possibly increased CNS stimulation from the higher level of androgens.