Towards improving post-SSRI sexual dysfunction by using nutriceuticals: Lessons from a case study

madman

Super Moderator
ABSTRACT
Post-selective serotonin reuptake inhibitors (SSRIs) sexual dysfunction (PSSD) is a new
clinical entity occurring after the antidepressant intake, and it is characterized by the fact that
patients continue to present sexual side effects after the discontinuation of the drugs. PSSD mainly
consists of hypo-anesthesia of the genital area, loss of libido, and erectile dysfunction. Although
different management options have been proposed, there is no consensus on the treatment for this
syndrome. Herein we report on a young man affected by PSSD who regained sexual functioning
after 3-month treatment with EDOVIS, a dietary supplement containing L-citrulline and other
commonly used aphrodisiacs.

Clinicians should be aware about the possibility of persistent sexual side effects induced by
serotoninergic antidepressants and take into considerations the use of nutraceuticals to overcome PSSD.






In conclusion, clinicians should be aware about the possibility of persistent sexual side
effects induced by serotoninergic antidepressants and take into considerations the use of
nutraceuticals, with regard to EDOVIS, to overcome PSSD and the related problems in sexual
relationship and quality of life.
 

Attachments

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
5
Guests online
207
Total visitors
212

Latest posts

Back
Top