Total T is up! But libido is gone....

Soilsample

New Member
Hello Gentlemen,
Please bear with me because getting proper blood tests with my Doc are like pulling teeth!

Anyway I'm 45.
5'10" and 235 pounds.
I weight train every day.... I'm overweight but built very solid with decent muscle mass.

Currently dealing with under active thyroid and low T.

Currently-
Test cyp 2000mg at 1ml every 2 weeks divided doses every 3.5 days. This has been going for 4 months.
Levothyroxene 112mg daily for thyroid (which is just now starting to function).

PROBLEM:
I saw my Dr today and he says my Total Test is up to 789 (tested in a trough before my Thursday injection) which sounds great. However he didn't test Free T or E2....
My problem is that I still feel like crap, and my sex drive has gone to ZERO.
He is sending me for another blood test for SBGH, Total Estrogen, and Albomin

I would greatly appreciate any advice or wise words!

thanks!
 
Last edited by a moderator:
Hello Gentlemen,
Please bare with me because getting proper blood tests with my Doc are like pulling teeth!

Anyway I'm 45.
5'10" and 235 pounds.
I weight train every day.... I'm overweight but built very solid with decent muscle mass.

Currently dealing with under active thyroid and low T.

Currently-
Test cyp 2000mg at 1ml every 2 weeks divided doses every 3.5 days. This has been going for 4 months.
Levothyroxene 112mg daily for thyroid (which is just now starting to function).

PROBLEM:
I saw my Dr today and he says my Total Test is up to 789 (tested in a trough before my Thursday injection) which sounds great. However he didn't test Free T or E2....
My problem is that I still feel like crap, and my sex drive has gone to ZERO.
He is sending me for another blood test for SBGH, Total Estrogen, and Albomin

I would greatly appreciate any advice or wise words!

thanks!

Sorry to hear about your docs insufficient testing. Discounted labs is great to supplement some missing lab test you need, say sensitive E2, because I'd put money on your doc NOT testing sensitive E2 if he's getting "total estrogen". Total estrogen is a completely worthless lab test.

As to why your libido is crap, is anybody's guess, as of now.
 
Hello Gentlemen,
Please bare with me because getting proper blood tests with my Doc are like pulling teeth!

Anyway I'm 45.
5'10" and 235 pounds.
I weight train every day.... I'm overweight but built very solid with decent muscle mass.

Currently dealing with under active thyroid and low T.

Currently-
Test cyp 2000mg at 1ml every 2 weeks divided doses every 3.5 days. This has been going for 4 months.
Levothyroxene 112mg daily for thyroid (which is just now starting to function).

PROBLEM:
I saw my Dr today and he says my Total Test is up to 789 (tested in a trough before my Thursday injection) which sounds great. However he didn't test Free T or E2....
My problem is that I still feel like crap, and my sex drive has gone to ZERO.
He is sending me for another blood test for SBGH, Total Estrogen, and Albomin

I would greatly appreciate any advice or wise words!

thanks!

Without further testing it's all a shot in the dark, a best guess. You need free testosterone, estradiol/sensitive test, SHBG, DHT, and, if it wasn't measured prior to therapy, prolactin. Then you need to find a new doctor. Failing to properly test is a dead giveaway that he/she doesn't understand androgen replacement. That is made even more clear by his ordering total estrogen. A total waste of time.

You deserve better.
 
I wish it was a simple thing to get a new Doctor.
Ive been struggling with this for over a year just to get where I am....

As much as I'd like to use one of the forum sponsors, I really want to use my insurance.

Its so so frustrating to spend over a year and get no true progress but it seems there are NO doctors in my area (SW Louisiana) that are any good at this game.

Ugh!!!!
 
I wish it was a simple thing to get a new Doctor.
Ive been struggling with this for over a year just to get where I am....

As much as I'd like to use one of the forum sponsors, I really want to use my insurance.

Its so so frustrating to spend over a year and get no true progress but it seems there are NO doctors in my area (SW Louisiana) that are any good at this game.

Ugh!!!!

You want to use your insurance to get substandard care? How many more months will go by with no improvement? I can't speak to your financial situation, but an investment in your health is worth, well, how much is it worth? Defy Medical may be cheaper than you imagine.
 
That's very good advice ^^^^ I agree.
If things don't get better quickly I'll be calling Defy!

and it's not likely that things will get much better if I can't even get proper testing.
 
That's very good advice ^^^^ I agree.
If things don't get better quickly I'll be calling Defy!

and it's not likely that things will get much better if I can't even get proper testing.

I'm not a Defy patient, I've no vested interest in their success, but I have great respect for Dr. Saya and the work they do. I wish you all the best. Keep us posted.
 
I have struggled with so many doctors that just couldn't get my protocol right and were unwilling to listen to me. I am now a patient of Dr Saya (Defy) and I couldn't be happier. I have never spoken to someone so knowledgeable in the field and so willing to help. If i were you I wouldn't think twice to call Defy. I still have a few things to fine tune but TRT has changed my life and I am really thankful to have found someone like Dr Saya to take care of my TRT protocol.
Even the smallest changes in your protocol might have drastic effects on how you feel. So it is imperative that you find someone that really knows about TRT and have some patience to fine tune your protocol.
Also this website is a very good source of information and everybody here is willing to help. A great TRT community! Thanks to Nelson Vergel! Best of luck!
 
Hello Gentlemen,
Please bare with me because getting proper blood tests with my Doc are like pulling teeth!

Anyway I'm 45.
5'10" and 235 pounds.
I weight train every day.... I'm overweight but built very solid with decent muscle mass.

Currently dealing with under active thyroid and low T.

Currently-
Test cyp 2000mg at 1ml every 2 weeks divided doses every 3.5 days. This has been going for 4 months.
Levothyroxene 112mg daily for thyroid (which is just now starting to function).

PROBLEM:
I saw my Dr today and he says my Total Test is up to 789 (tested in a trough before my Thursday injection) which sounds great. However he didn't test Free T or E2....
My problem is that I still feel like crap, and my sex drive has gone to ZERO.
He is sending me for another blood test for SBGH, Total Estrogen, and Albomin

I would greatly appreciate any advice or wise words!

thanks!

Everyone is different but i only felt really good when my Total Testosterone went over 1000 ng/dl (with free testosterone over 25 pg/ml) amd estradiol between 20-30 pg/ml (estradiol being the most difficult thing to get right). As odd as it might sounds estradiol within range was key for libido and energy (a "female" hormone responsible for libido in men might sound odd). HCG didnt really change how i felt to be honest but i added because i wanted to remain fertile (still trying to get there).
 
Everyone is different but i only felt really good when my Total Testosterone went over 1000 ng/dl (with free testosterone over 25 pg/ml) amd estradiol between 20-30 pg/ml (estradiol being the most difficult thing to get right). As odd as it might sounds estradiol within range was key for libido and energy (a "female" hormone responsible for libido in men might sound odd). HCG didnt really change how i felt to be honest but i added because i wanted to remain fertile (still trying to get there).

I'm curious, are you on AI? I only ask because if you need to be at 1000 to have a 20-30 E2 level that's an even lower aromatizer than myself, and I thought I was low!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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