Timeline of HCG's effects on testosterone levels

[Teston]

I see a lot of info out there regarding the timeline and serum levels of testosterone after injecting, but am having a hard time finding similar info for HCG.

Anyone know how long it takes for an injection of HCG to impact T levels? Is there a similar onset/peak for increased T or is it specific to the dosage and/or individual? I suspect it's longer due to having to go through more steps before T is manufactured in the testes, but I figured someone here may actually know.

I guess I'm looking for something similar to the cypionate peak levels chart I've seen everywhere, but showing T levels after an HCG injection instead.

 

[Dreams]

I think this is what you're looking for:

https://www.researchgate.net/figure...el-and-testosterone-levels-lower_fig1_5353977

 

[Vince]

I really think it's different for everyone, especially if your primary. Your testicles would be making very small amount of testosterone, compared to somebody who's secondary, he would make a lot more testosterone.

 

[MarkM]

Welcome to the forum. I believe the link posted by Dreams is for normal men so if you have primary hypogonadism or secondary hypogonadism the results may not be the same.

In fact, if you have primary hypogonadism the HCG isn't going to have much, if any, impact on increasing your T levels. Most people that have primary hypogonadism taking HCG are doing it to try to prevent testicle atrophy and in an attempt to back fill the hormonal pathways.

If you have secondary hypogonadism it depends on factors such as how long you have been on T, how long you have been on T prior to taking HCG, and of course your individual body chemistry because even under identical situations we all will react differently to HCG.

For example, I have secondary hypogonadism and was on TRT about 12 years before using HCG. Honestly, I did not even know about HCG or its potential benefits because no doctor ever discussed it with me. Because I was on TRT for so many years without HCG I believe it is probably not doing much for me in increasing T levels. My testing shows no difference in T levels with or without it and I really don't notice any improvement in testicular atrophy. Had I been on HCG earlier on in my TRT protocol that might all be different. The only reason I take it now is to try to back fill the hormonal pathways which I feel is important but in my testing I have not seen that to be the case.

My recommendation for anyone going on TRT would be to at least try the HCG because it benefits a great many people, especially if one is trying to remain fertile. HCG has a short half life of about 48 to 50 hours and I think it would have the largest impact on T levels between 48 and 72 hours depending on the individual.

We've got some really knowledgeable individuals on the forum and I am sure some of them with much greater knowledge than I will weigh in for you and correct any misinformation I may have given.

 

[Teston]

Y'all continue to be a fantastic resource. I love this site.

 

[jdthoosier]

Adding HCG has made a big difference for me. Not only is my testicle atrophy is gone, but my estradiol levels are more robust (I struggled with estradiol levels in the teens) and my libido /ability is much improved. However, as far as impacting T - minimal in my case.

 

[Vince]

For whatever reason no matter how low my estradiol levels have been my libido is always strong. I've never used an AI, my estradiol levels are just naturally low. Even before I started trt and they were basically unreadable my libido was still very high.

 

[Teston]

Welcome to the forum. I believe the link posted by Dreams is for normal men so if you have primary hypogonadism or secondary hypogonadism the results may not be the same.

In fact, if you have primary hypogonadism the HCG isn't going to have much, if any, impact on increasing your T levels. Most people that have primary hypogonadism taking HCG are doing it to try to prevent testicle atrophy and in an attempt to back fill the hormonal pathways.

If you have secondary hypogonadism it depends on factors such as how long you have been on T, how long you have been on T prior to taking HCG, and of course your individual body chemistry because even under identical situations we all will react differently to HCG.

For example, I have secondary hypogonadism and was on TRT about 12 years before using HCG. Honestly, I did not even know about HCG or its potential benefits because no doctor ever discussed it with me. Because I was on TRT for so many years without HCG I believe it is probably not doing much for me in increasing T levels. My testing shows no difference in T levels with or without it and I really don't notice any improvement in testicular atrophy. Had I been on HCG earlier on in my TRT protocol that might all be different. The only reason I take it now is to try to back fill the hormonal pathways which I feel is important but in my testing I have not seen that to be the case.

My recommendation for anyone going on TRT would be to at least try the HCG because it benefits a great many people, especially if one is trying to remain fertile. HCG has a short half life of about 48 to 50 hours and I think it would have the largest impact on T levels between 48 and 72 hours depending on the individual.

We've got some really knowledgeable individuals on the forum and I am sure some of them with much greater knowledge than I will weigh in for you and correct any misinformation I may have given.

This has me thinking, it seems HCG creates a lot of concern around elevated estradiol levels. If I understand the above correctly, that HCG induced elevation should only be happening in secondary men, since estradiol is created downstream from testosterone. Right?

 

[Vince]

This has me thinking, it seems HCG creates a lot of concern around elevated estradiol levels. If I understand the above correctly, that HCG induced elevation should only be happening in secondary men, since estradiol is created downstream from testosterone. Right?

I would have to agree with you, I believe when men are primary they do not have any estradiol issues when using HCG. I guess we need to start a thread on men who are primary and use HCG.

 

[Nelson Vergel]

Read this

Does HCG promote excessive aromatization while on TRT?