Thyroid Interpretation of results

TonyG

Member
Hey guys,

I'd like your input on whether I need Thyroid treatment or not. I'm 33 years old. My TSH has always been high since before starting TRT in my late twenties. I've posted all labs below in order from the most recent to the oldest. I am experiencing moodswings (2 days good, 5 days bad) but I am also 14 weeks in to a protocol change so I am attributing the moodswings to that.

3-29-21.webp

3-29-21(1).webp

3-29-21(2).webp


1-4-21.webp

6mo.webp

2018.webp


3 months into TRT.webp

preTRT.webp
 
Hey guys,

I'd like your input on whether I need Thyroid treatment or not. I'm 33 years old. My TSH has always been high since before starting TRT in my late twenties. I've posted all labs below in order from the most recent to the oldest. I am experiencing moodswings (2 days good, 5 days bad) but I am also 14 weeks in to a protocol change so I am attributing the moodswings to that.

View attachment 13558
View attachment 13559
View attachment 13560

View attachment 13565
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post # 31/36/37


Your trough TT (LC/MS-MS) and FT (Equilibrium Ultrafiltration) levels are still high just as they were on your last set of labs.

The only difference on the last set of labs you were not taking the AI and your e2 (LC/MS-MS) was absurdly high due to your high FT/lowish SHBG.

Instead of dropping your overall weekly T-dose slightly to bring down your TT/FT which would also result in a lowering of your estradiol you went and hopped on the AI again as it now hovers around 17.

Not only are your trough TT/FT levels still high but you drove your estradiol down from an absurdly high 90--->17.....go figure!
 
Last edited:
post # 31/36/37


Your trough TT (LC/MS-MS) and FT (Equilibrium Ultrafiltration) levels are still high just as they were on your last set of labs.

The only difference on the last set of labs you were not taking the AI and your e2 (LC/MS-MS) was absurdly high due to your high FT/lowish SHBG.

Instead of dropping your overall weekly T-dose slightly to bring down your TT/FT which would also result in a lowering of your estradiol you went and hopped on the AI again as it now hovers around 17.

Not only are your trough TT/FT levels still high but you drove your estradiol down from an absurdly high 90--->17.....go figure!
Yes all of that is correct but what does that have to do with the thyroid? I am eventually going to drop my T-dose like we discussed but first i want to feel good. Hoping things stabilize as i approach 16 weeks (4 months) on this protocol.

What are your thoughts on the thyroid numbers?
 
Your numbers have always been good, but now TSH's half high. I would wait some time and then redo the tests if i don't have symptoms of hypothyroidism, and i'd also do anti-tpo test
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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