Thoughts on protocol change

SixHouse

Member
I've been doing 50mg Cypionate 3x per week (150mg per week total) for a long time. Wondering if anyone thinks there would be any noticeable, negative difference if I changed to 75mg 2x per week.
 
SHBG is usually around 41. I didn't mention anything else because I intentionally want to abstract it. Assume nothing else. I'm only looking for a very general opinion on whether or not the change in Cypionate schedule might be felt in a negative way.
 
There's no reason to change when there is nothing wrong. Though something like this there's unlikely going to be anything profound occur good or bad, can just be preference to how much oil you want to inject at each shot or simply reduce from 3 shots to 2.
 
There's no reason to change when there is nothing wrong. Though something like this there's unlikely going to be anything profound occur good or bad, can just be preference to how much oil you want to inject at each shot or simply reduce from 3 shots to 2.

Well that's subjective. The reason for my change is simply to make life easier. I'd rather inject twice a week than 3 times a week. I travel a lot so twice a week makes things much easier.
 
In the abstract, hormonal peaks will be a little higher, and troughs a little lower. The magnitude of the estradiol oscillations may increase a little more than in proportion to the testosterone increase. Average testosterone and estradiol levels shouldn't change.
 
im new but have hours and hours into research ...so correct me if im wrong but wont changing protocol fluctuate everything for another 6 weeks till he's stable again ???
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
1
Guests online
322
Total visitors
323

Latest posts

Back
Top