The ups and downs of my TRT protocol with Nebido

Kristian

New Member
Hi there!

I started TRT with NEBIDO in July 2016. I live in Norway, and Nebido seems to be the preferred method here. There has been many challenges for me the last 6-7 months with fine-tuning my protocol, I hope things will be better for me in the coming months.

Let me give you some a brief background here. I am 41 years old. I think I always had low testosterone, and my bloodwork before starting Nebido, showed I was in the lower “normal” ranges.

Anyway, I started with Nebido injections every 8 weeks, as suggested by the doctor. The first months were ok (but not great), and then I started feelings symptoms of high estradiol – puffy nipples. And I felt like shit too – I might add! I then took new bloodwork in early December to confirm this (results attached). Anyway, I then started treating this problem with nolvadex and arimidex, and the “gyno” symptoms are now gone.

I do feel much better after starting a very low dose of arimidex (0,25 mg twice a week). I will do new bloodwork late February/early March to measure the effects or adjust as necessary.
So, I could elaborate with much more detail here, but I hope this gives you necessary background to comment on my questions:

1. I have started splitting my NEBIDO injections into 1 weekly injections instead (0,5 ml/125mg test undecanoate). This should be ok?

2. I do feel much better now, but my libido/sex drive is not as good/high as I had hoped. What could be the reason for this?

3. I read Jay Cambell's book recenctly (The Definitive Testosterone Replacement Therapy MANual), and he recommends using Stinging nettle root. I ordered some bottles of this already, but I also did a bit more reading about this herbal supplement. For some it gives no effect, for others it helps boost libido and others claim it can cause elevated estradiol as well. I am clearly not interested in the latter.

Anyway, I realize you will need updated bloodwork here – and I will try to update this thread with new information and new results of bloodwork later this month or early march.

Thanks for reading and thanks for a great forum!
 

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It would be nice to see your upcoming labs. Are you supplementing with on vitamins. I would consider adding D3.
 
Hi Vince!
I do take D vitamins actually. A lot of Norwegians are deficient in this vitamin (not too much sun here in the winter:-) ).
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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