Testosterone & Beyond: The New Science of Men’s Health, Recovery, and Longevity

[madman]

Synthesis and Conclusions

 

[madman]

Age Great Schism: Roots of Academic Dogma and Controversy

 

[madman]

Bhasin's groundbreaking 96 study!




The Effects of a Supraphysiologic Dose of Testosterone without and with Resistance Exercise Training in Healthy Men

Testosterone's Effects on Fat-Free mass in Healthy Men with Severe Hypogonadism

The TEAAM Trial

Several other RCTs

Anabolic Effects of Testosterone in Men with HIV-Associated Weight Loss and COPD

T Dose Response in Young and Older Men: Changes in Fat Free Mass

 

[madman]

Doses well beyond therapeutic 300-600 mg/week is where Ts true anabolic potential really starts to shine especially changes in Type 1 fiber/satellite cell number!




Mechanisms of Androgen Action on the Muscle: Testosterone Induces Muscle Fiber Hypertrophy

Testosterone Promotes Myogenic. Differentiation of Mesenchymal Progenitor cells vying Activating Target Genes

 

[madman]

Additional Mechanisms by which Testosterone may Improve Physical Performance

 

[madman]

Targeting Multiple Levels of AR Interactive to Achieve Selectivity of Action and Improve Benefit-Risk Ratio

Conversion of T to DHT is not essential for mediating its anabolic effects

Selective Androgen Receptor Modulators

 

[madman]

Potential Reasons for the Failure of Promyogenic Drugs to Secure Regulatory Approval

 

[madman]

Can Increased Protein Intake Augment Anabolic Effects of Testosterone Treatment

 

[madman]

The Important Role of Neural Input in Mediating the Anabolic Effects of Anabolic hormone such as Testosterone

 

[madman]

The XPRIZE Boston Healthspan Extension Trial

Thread 'Brigham Researchers Advance to Next Phase of International XPRIZE Healthspan Competition'

Jun 22, 2025

* The winning team must demonstrate that their therapeutic treatment restores muscle, cognitive and immune function in persons aged 50 to 80 years.

Brigham Researchers Advance to Next Phase of International XPRIZE Healthspan Competition

The XPRIZE award includes $250,000 to fund preliminary studies and a chance to compete for the $101 Million grand prize.

mgriblog.org

The XPRIZE award includes $250,000 to fund preliminary studies and a chance to compete for the $101 Million grand prize to revolutionize the approach to human aging.

...

• madman
• human aging;; healthspan; research
• Replies: 5
• Forum: Health & Wellness

 

[madman]

Synthesis and Conclusions