TestoGel / Creams etc: how long can you keep a stable serum level?

krm

Member
I was wondering - Gels etc. have very short half-lives, usually a few hours from what I've read in studies like this one.

Would that mean - if I go on a business trip abroad for a few days and happen to forget my gel, I'm in for a miserable experience because after 24-48 hours, stuff has basically been cleared from my system and due to my own production being shut down, I'm out of luck?
 
Everyone is different and I am sure there are some that would feel it. I was on gels for years and traveled 45 weeks out of the year. There were times I forgot to pack my Androgel and had to go with our for the better part of the week. I don't recall having a terrible experience and I am sure I would remember if it was all that bad.

In all those years I maybe forgot it two or three times early on in my TRT. Somehow, things that become important to us we tend to remember.
 
When I took gels my levels fluctuated daily. One day I might take a blood test and be 325 TT. The next day back down to 157 TT. It’s in and out fast, at lest for me.
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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