Supplementing T4 with thyroid Labs

Do you take any T4? What is your FT4 level on T3 only? Tx
I do, but only because my Primary Care doc insists on it. Early on when I was just taking T3 prescribed by Defy, my FT4 level was about 0.8 and my PCP thought it needed to be higher. After adding 75 mcg of T4, my FT4 actually dropped to anywhere from 0.4 to 0.6. I feel no different with or without T4. For me it was adding T3 that made all the difference.
 
I do, but only because my Primary Care doc insists on it. Early on when I was just taking T3 prescribed by Defy, my FT4 level was about 0.8 and my PCP thought it needed to be higher. After adding 75 mcg of T4, my FT4 actually dropped to anywhere from 0.4 to 0.6. I feel no different with or without T4. For me it was adding T3 that made all the difference.
Thanks! Are you taking all 50 mcg T3 at one time in the morning?
 
Thanks! Are you taking all 50 mcg T3 at one time in the morning?
I split the dose. These days I take 25 mcg upon waking, then another 12.5 mcg mid-day. Occasionally I will forget to take the mid-day dose if I'm busy, and have never felt any worse than if I had remembered to take it.
 
Hey guys. I got my thyroid numbers today. In my country we get levothyroxine without prescription in pharmacies. I am thinking about supplementing T4 to bring my TSH between 1-2.
What dose should I start with. 25 mg or better 50.
Since starting TRT my TSH is climbing continuously.

TSH: 2.23
FT3: 3.3
FT4: 1.03

Even tho I war the same amount of calories daily it’s getting harder and harder to stay on the same body fat percentage. I have to cut down more and more and if it continues like that I would need to go under 1700 calorie’s which is not optimal.

In my country they just treat you if you are above 6. So talking to my doctor would lead to nowhere.

So how should I supplement T4?
Edit---: i felt best when my TSH was 1 before TRT even tho my T4 was 0.9.

Hey, have you started supplementing already? I'm also considering doing something about this. Have just gotten my results back.
  • TSH: 3.72 (0.27 - 4.20 mIU/L)
  • FT3: 4.8 (3.1 - 6.8 pmol/L)
  • FT4: 14.8 (12.0 - 22.0 pmol/L)
Have you checked your ferritin levels? Mine are suboptimal (around 60 ng/mL). This likely hampers thyroid function some.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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