Sub Q Testosterone injections

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Mando

Member
Is anyone aware of any recent studies that I can present to my doctor about Sub Q vs Intramuscular shots. I would like to try Sub Q, but want to be able to provide my doctor with some info on my next visit.

Also, any evidence that Sub Q can lower estrogen levels?

I am currently on IM 150mg/week split into two doses. I would like to try the Sub Q route to avoid repeated injections into the muscle and possibly lower estradiol levels.

My sensitive estradiol is 41 on the 10-40 scale. Was measured on the Monday morning before my shot was due (my injection schedule is Monday AM and Thursday PM)

Or would you all just stick with IM? Currently I am doing ventrogluteal with a 25 gauge, 5/8" needle.

Thanks.
 
Defy Medical TRT clinic doctor
None of that really matters at all the only thing between IM and SQ has to do with the size of the needle. SQ allowed us to start using smaller and shorter needles like the 29g 1/2" U100 insulin syringe. Larger and longer needles are used for IM.

If you're self injecting at home no one is going to know the difference except you.
 

Nashtide

Member
None of that really matters at all the only thing between IM and SQ has to do with the size of the needle. SQ allowed us to start using smaller and shorter needles like the 29g 1/2" U100 insulin syringe. Larger and longer needles are used for IM.

If you're self injecting at home no one is going to know the difference except you.
You can order really inexpensive insulin syringes or buy them from Walmart.
 

Mando

Member
Have you had any noticeable difference with estrogen levels? I have heard Dr. Crisler say that SQ can actually lower estrogen levels.

And yes, I am self injecting.

None of that really matters at all the only thing between IM and SQ has to do with the size of the needle. SQ allowed us to start using smaller and shorter needles like the 29g 1/2" U100 insulin syringe. Larger and longer needles are used for IM.

If you're self injecting at home no one is going to know the difference except you.
 

Mando

Member
How do you measure dosage with the insulin syringes. I use the tuberculine syringes that are marked in 0.01 cc increments. How are your insulin syringes marked and how for instance would you do a dosage of 35 mg since the insulin are typically in 2 "units" from what I understand.

Thanks.
 
Last edited:

Nashtide

Member
How do you measure dosage with the insulin syringes. I use the tuberculine syringes that are marked in 0.1 cc increments. How are your insulin syringes marked and how for instance would you do a dosage of 35 mg since the insulin are typically in 2 "units" from what I understand.

Thanks.
The insulin syringes I use are 1cc(ml). Marked in increments of a tenth of a cc or ml. My T cyp is 200mg/ml. So to draw up 35mg you would fill the syringe to the area halfway between 17 and 18. That's 17.5ml or 35mg.
 
Have you had any noticeable difference with estrogen levels? I have heard Dr. Crisler say that SQ can actually lower estrogen levels.

And yes, I am self injecting.

Even with Dr C in my high regard any such statement is purely anecdotal, not supported by science, and has no testing to back it up.
 

madman

Super Moderator
Is anyone aware of any recent studies that I can present to my doctor about Sub Q vs Intramuscular shots. I would like to try Sub Q, but want to be able to provide my doctor with some info on my next visit.

Also, any evidence that Sub Q can lower estrogen levels?

I am currently on IM 150mg/week split into two doses. I would like to try the Sub Q route to avoid repeated injections into the muscle and possibly lower estradiol levels.

My sensitive estradiol is 41 on the 10-40 scale. Was measured on the Monday morning before my shot was due (my injection schedule is Monday AM and Thursday PM)

Or would you all just stick with IM? Currently I am doing ventrogluteal with a 25 gauge, 5/8" needle.

Thanks.

Regarding absorption/effectiveness there should be no difference between injecting sub-q (adipose) or i.m.(muscle).

If your doctor is stubborn or you feel would be ill convinced, seeing as you are self injecting than try sub-q yourself.

Whether one chooses to inject subcutaneous or intramuscular really comes down to personal preference and which method is the most comfortable/least painful.

As far it being said that injecting sub-q will lower ones e2 I would not hold any weight to it as it has never been proven .

I would say injecting lower doses of testosterone more frequently will have an impact on less e2 conversion, mind you it all comes down to the individual, testosterone dose/frequency, body fat levels, shbg /free t levels and of course ones genetics as believe it or not some are just naturally high converters of t--->e2 (even lean individuals).
 

Bobcat 9

New Member
Just my experience.

Is anyone aware of any recent studies that I can present to my doctor about Sub Q vs Intramuscular shots. I would like to try Sub Q, but want to be able to provide my doctor with some info on my next visit.

Also, any evidence that Sub Q can lower estrogen levels?

I am currently on IM 150mg/week split into two doses. I would like to try the Sub Q route to avoid repeated injections into the muscle and possibly lower estradiol levels.

My sensitive estradiol is 41 on the 10-40 scale. Was measured on the Monday morning before my shot was due (my injection schedule is Monday AM and Thursday PM)

Or would you all just stick with IM? Currently I am doing ventrogluteal with a 25 gauge, 5/8" needle.

Thanks.

When I switched doctors and switched from IM to sub-q my estradiol level lowered (a lot). And I began feeling better - more energetic, more stamina, morning erections, overall positive mood - almost immediately. Now, 7 months down the road from when I started sub-q I'm still feeling the same positive results.
 

Pumpiniron13

New Member
Everyone is different and metabolizes injections differently. My personal experience was my body didn’t absorb T sub q as well as IM. Felt fine day of injection and felt super lathergic until next pin. Went back to IM PIN and felt fine, revisited sub q pin with same results as first try. I now do 3 pins IM WEEKLY and estrogen and hematocrit are both managed.
 

Vince

Super Moderator
I never was a fan of Sub-Q, I really like using Easy Touch syringe and shallow IM the method I learned from watching Nelson's video.
 
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