Splitting Nebido

Has anyone tried to split Nebido (long acting T) and inject, say 0.5 ml per week? How did it work for you?

You are completely defeating the purpose of the long acting ester. If you plan on just injecting weekly the pharmacokinetics of enanthate/cypionate esters will suffice for many although every 3.5 days is better for most.
 
You are completely defeating the purpose of the long acting ester. If you plan on just injecting weekly the pharmacokinetics of enanthate/cypionate esters will suffice for many although every 3.5 days is better for most.
Absolutely right, but sadly I don't think he access to either.
 
Absolutely right, but sadly I don't think he access to either.
Yes, spot on. I may (based on symptoms) have high E2. The sensitive test is not available here. So, I am trying to find a solution. I've got a Nebido ampule. Should I give it a try? May be better than a multi-ester one?
 
You are completely defeating the purpose of the long acting ester. If you plan on just injecting weekly the pharmacokinetics of enanthate/cypionate esters will suffice for many although every 3.5 days is better for most.
Can I try a tiny dose of an AI? See if it works?
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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