Thanks @madman11:50-13:55 (5-alpha reductase enzyme family)
*it's also involved in the formation of dihydroprogesterone and dihydrotestosterone and even has a part in the formation of the 3-alpha diol which has an impact on the estrogen receptor
*so those steroid hormones even neurosteroid hormones are having an impact on two very major receptors in our brain and these receptors/these hormones have not only endocrine function in all our body they also have paracrine and autocrine effects in our brain in the cells near and the cells where they are produced so these neurosteroid hormones have tremendous effects in our brain
Predict estradiol, DHT, and free testosterone levels based on total testosterone
This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.
Enter your total testosterone value to see predictions
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038