Risk factors for acne development in the first 2 years after initiating masculinizing testosterone therapy among transgender men

madman

Super Moderator
Several existing studies have shown that transgender men experience increased sebum production and acne with testosterone therapy. The virilization effects of testosterone in transgender men, both systemic and dermatologic, are somewhat variable in intensity and timing after the initiation of testosterone therapy. Additionally, individual goals for testosterone therapy range from maximum virilization to suppression of feminizing secondary sex characteristics only. Nakamura et al reported that during the first 6 months only, the most commonly desired virilization effects were dose dependent. If a transgender man begins to develop acne, it may be possible to personalize his testosterone therapy depending on transition goals, priorities, risk factors, and other comorbidities.
 

Attachments

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
5
Guests online
213
Total visitors
218

Latest posts

Back
Top