https://www.excelmale.com/forum/showthread.php?2523-DHEA-Supplementation-What-Do-Studies-ShowSounds like DHEA is wonderful. Should we be using it with our HRT regimen?
DHEA to me I take the same position on it as Anastrzole, should never be a basic inclusion in some one's protocol and not even based on testing, it should be used with caution. As my friend CW posted it can be wrought with E problems for some guys no matter what form or how it's taken. Often dosed too high, too 2 25-50mg. Anyone using DHEA should consider a low 5-10mg dose that tirates upward based on tolerance. Just because a test reads "low" doesn't mean you need it or should take it.
I was excited to add it to my protocol a while, a good while, ago and my doctor asked me to explain why it was necessary. My levels were normal, I'd brought my E2 into line without an AI and I felt great. When she put it that way, and after digging in and seeing some of the problems guys here report with it, I realized it wasn't in my future.
Predict estradiol, DHT, and free testosterone levels based on total testosterone
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A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.
Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.
The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.
Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.
DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038