Join Dr. Jared Pelo and Shalin Shah for an in-depth discussion about revolutionizing testosterone therapy. Shah, with his extensive background in healthcare investment and drug development, shares insights about Kyzatrex, an innovative oral testosterone medication, and discusses why testosterone has been misunderstood in medicine.
Learn about:
* Why testosterone was historically vilified and how recent research is changing perspectives
* The groundbreaking Traverse Study and its implications for cardiovascular health
* How daily oral testosterone better mimics the body's natural rhythm compared to injections
* The critical role of testosterone in metabolic health, diabetes prevention, and longevity
* Why testosterone testing should be standard in preventive care
* The future of hormone therapy for both men and women
Key Timestamps:
00:18 - Shalin's journey into testosterone research and development of Kyzatrex 03:18 - Understanding oral testosterone and debunking liver toxicity myths 06:03 - Historical misconceptions: Why testosterone was unfairly vilified 11:04 - The Traverse Study (2023): Proving cardiovascular safety 13:28 - T4DM Study: Testosterone's impact on diabetes prevention 15:22 - Why daily oral testosterone better mimics natural body rhythms 24:05 - The Testosterone Project's three initiatives:
Making testosterone testing standard
Creating FDA-approved options for women
De-scheduling testosterone
36:09 - Why Kyzatrex chose a cash-pay model for better access
In this episode of The Dr. Gabrielle Lyon Show, Dr. Lyon sits down with Shalin Shah, CEO of Marius Pharmaceuticals, to explore the science, benefits, and future of testosterone therapy. Shalin has been a driving force behind bringing Kyzatrex, an FDA-approved oral testosterone, to market—making testosterone therapy more accessible and effective for both men and women. From breaking down misconceptions to advocating for better access to hormone therapy, this conversation sheds light on how testosterone plays a crucial...
Hypogonadism, characterized by low testosterone levels, is a significant clinical condition affecting a substantial proportion of the male population, particularly older men. The management of hypogonadism often involves testosterone replacement therapy (TRT), which can be administered through various routes, including intramuscular injections, transdermal patches, and oral formulations. While injectable and transdermal options have been extensively studied, oral testosterone therapy, particularly using testosterone undecanoate (TU)...
*one of the things that the orals have transformed is the concept that you have to have a continually high level of testosterone to get the benefits and clearly that's not true and the safety profile seems to be improved by having levels that fluctuate some during the day returning to close to or even baseline
Synopsis
Dr. Morgentaler starts by sharing his pioneering journey with...
Pros/Cons oral TU (51:24-57:12)
*one of the things that the orals have transformed is the concept that you have to have a continually high level of testosterone to get the benefits and clearly that's not true and the safety profile seems to be improved by having levels that fluctuate some during the day returning to close to or even baseline
Hayden Collier, PharmD is the director of clinical services at nuBioAge. He is committed to advancing healthcare through innovative, patient-centered approaches. With a passion for weightlifting, he draws parallels between the discipline of fitness and the importance of prevention in modern medicine. Hayden’s expertise extends beyond the pharmacy, blending sports science with cutting-edge medical strategies to redefine how we approach health and longevity. A dedicated husband, father, and sportsman, he brings the same focus and energy to both personal and...
In this episode, host McCall McPherson discusses a breakthrough in testosterone therapy with Shalin Shah, CEO of Marius Pharmaceuticals. They explore the development and benefits of Kyzatrex, a new oral testosterone replacement therapy. Shalin shares his journey into the testosterone space and highlights the importance of testosterone for overall health. They address the prevalence of low testosterone, its symptoms, and the limitations of traditional therapies. Kyzatrex offers a safer, more effective alternative with stable hormone levels and fewer...
Shalin Shah and his company's product have totally changed my opinion about TRT. I had a ton of misconceptions about testosterone replacement therapy. My thoughts have changed, and I think you'll find this episode very revealing.
In this episode we cover:
-The difference between oral and injectable testosterone
-Dispelling the myths about TRT
-Determining the minimum effective dose for TRT dosage
What if there was a pill that could increase testosterone without injections or topical applications? In this episode, Dr. Geo Espinosa sits down with Shalin Shah, a leader in metabolic health and CEO of Verity Pharma, to discuss oral testosterone therapy and the FDA-approved drug Kyzatrex.
* Does this new pill actually work?
* How does it affect SHBG & free testosterone?
* What are the side effects compared to injections & gels?
* Can it help prevent muscle loss with GLP-1 agonists like Ozempic?
In this KYZATREX webinar, Dr. Andrew Sun explores the evolution of testosterone therapy and the growing role of oral options. He reviews clinical data on KYZATREX, discusses treatment considerations, and shares practical tips for managing patient expectations when starting oral testosterone therapy.
KYZATREX (testosterone undecanoate) is a prescription drug that is used to treat adult men who have low or no testosterone levels due to certain medical conditions.
