Recent labs....

[robs2nd75]

Does anyone have any thoughts in regards to hyperparathyroidism and/or T3 supplementation?

[h=4]Lab Test Results[/b] acth, plasma

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insulin

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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triiodothyronine,free,serum

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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thyroxine (t4) free, direct, s

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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cortisol

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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vitamin d, 25-hydroxy

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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hemoglobin a1c

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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comp. metabolic panel (14)

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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lipid panel

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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igf-bp3

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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igf-1

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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antithyroglobulin ab

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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thyroid peroxidase (tpo) ab

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

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tsh

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[/TD]

 

[Gene Devine]

Vette is your best for this response Rob.

 

[Vettester Chris]

Rob, I can see your concern with the higher calcium number. You need a PTH lab. Are you noticing any uncomfortable sensations in the thyroid region?

Your FT3 is at the upper end of the range, FT4 towards the middle. Are you on any NDT or other thyroid meds at this time? With FT3 that high, we really need a Reverse T3 to compare and make sure it's not just building up and pooling. Antibodies look good IMO.

Hemoglobin is up there. Donate blood regularly to regulate RBC's & HCT. Look to see where your iron serum, TIBC, ferritin and B12 are at as well. Also, It's hard to make much of 1x cortisol serum lab. Depending on the time of day that thing can be all over the place. Cortisol 4x looks to be the gold standard these days.

 

[robs2nd75]

Thank you kindly for your input. It's greatly appreciated. Doing PTH, Magnesium and w/e other labs she's ordered this am. I know ferritin is good I am a carrier for Hemocromatosis (sic) but it's been checked a few times and is fine. This is the second cortisol test and both have been normal but I completely agree on the 4x test. I'm fairly certain I have hyperparathyroidism from the side effect profile but the cause is a ?. I am not on any throid meds at this time but she did prescribe T3 to help with weight...should I take this or wait for PTH issue to be resolved? I will push for more tests as these results return. Thanks again for your time and thoughts.............rob

 

[Vettester Chris]

If it were me, I'd hold off on the T3 meds based on your labs. You are already sitting at 91% of your reference range on T3, not sure why the doctor would want to add more (?). Again, the next step on that subject IMO is getting your Reverse T3 lab and compare the ratio with FT3. Fair chance you are pooling T3 based on the fact that these are your baseline numbers. Let us know on your upcoming labs. BTW, I am also a carrier with hemochromatosis.

 

[robs2nd75]

PTH labs....

[h=4]Lab Test Results[/b] pth, intact

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

[/TD]

calcium, serum

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

[/TD]

magnesium, serum

[TD="class: ccrCol1"] [/TD] [TD="class: ccrCol2"]

[/TD]

 

[Nelson Vergel]

Better than before for sure!

 

[robs2nd75]

Better than before for sure!

Calcium keeps increasing. From what I've read PTH should be close to zero when calcium is elevated. Wondering what effect hypercalcemia has in the gym? I am constantly sore and have had numerous injuries. Can I safely say this is due to hypercalcemia?
Thank you all for your responses!!!!

 

[Vettester Chris]

Rob, it's hard to say. The only other thing I can think that might be tied in with it is excessive Vitamin D3. Your D lab doesn't look all that excessive, so again, it's just speculation. I'd possibly look at getting a referral to specialist, who can take a 2nd run at your parathyroid glands. Your PTH is on the lower end, so I would want another opinion if any of your glands need a further evaluation.

 

[Nelson Vergel]

Robs2nd75

I am not sure if you have posted your CPK blood levels. Have you? CPK increases with exercise but in some men it can increase excessively which can result in lots of body aches and slower recovery from exercise.

Do you know your CPK level? It can alert you about potential muscle and tendon tears

 

[Nelson Vergel]

Robs2nd75

One more thing (I apologize if you posted it somewhere else). Can you post your medication list if you do not mind? (Include supplements) Thanks

 

[robs2nd75]

Robs2nd75

I am not sure if you have posted your CPK blood levels. Have you? CPK increases with exercise but in some men it can increase excessively which can result in lots of body aches and slower recovery from exercise.

Do you know your CPK level? It can alert you about potential muscle and tendon tears

I think the last one I had was about a year ago and levels were normal but I will get them to run it again. Endo is going to have me do a sestamibi scan for parathyroid growth/s. I decided yesterday afternoon to go ahead and take the T3 and this morning I woke up energized, in a good mood (more calm), and the majority of body pain was gone. Does anyone know why this would be?

 

[robs2nd75]

Robs2nd75

One more thing (I apologize if you posted it somewhere else). Can you post your medication list if you do not mind? (Include supplements) Thanks

Methylphenidate, Bupropion, naltrexone, amlodipine, lisinopril-hctz (may be cause of hypercalcemia), metformin, glipizide, T. cyp, anastrozole (.25mg q3.5d), just started T3, Jarrow 1-2-3 multi, vitamin D 5k one day 10k the next, fish oil 1200 mg 3 x day..... rediculous list I realize

 

[robs2nd75]

Any thoughts on these meds/sups Nelson or anyone else?

 

[Nelson Vergel]

Robs2nd75


Don't feel bad about taking all those medications. You should see my list!! I win.


So you are taking two uppers (generic Ritalin and Wellbutrin), three blood pressure meds (a calcium channel blocker, an ACE inhibitor and a diuretic), two glucose control meds, naltrexone, testosterone, anastrozole and supplements.

Have you noticed any significant weight loss with bupropion+ naltrexone + metformin? This is a combo that can be effective in weight loss. Weight loss will decrease the need of taking the blood pressure and glucose control meds eventually.

I have definitely seen an improvement in muscle aches with supplementing Coenzyme Q-10 at 300 mg per day and Carnitine at 2000 mg per day. I am not sure if you have tried that combo that is not only cardio protective but that seems to keep our mitochondria working well.

I have heard men on diuretics complain about muscle aches. Could it be related to dehydration?

How are you feeling this week?

 

[robs2nd75]

I am feeling quite a bit better since starting T3. I still have some muscle soreness but nothing like before. The naltrexone combo has helped me lose about 25 lbs but its effectiveness has worn off so I discontinued it when I started the T3. Allowing it to completely get out of my system before reintroducing it. In terms of the diuretic, I drink at a minimum, a gallon of water a day and I almost never have headaches so dehydration is questionable at best. From what I've read thiazides (sic) can wreak havoc on minerals. I am going to find out what exactly is causing the hypercalcemia before introducing anything else but I greatly appreciate the advice.

 

[bruin]

OPTIMUM REQUIRED LAB WORK (Preferred but not mandatory)

1 ------- CAH Panel 6B (Comprehensive Screen) (10299X)
2 17.4 Estradiol- ultrasensitive [4021X](13- 54 pg/mL)
3 ------- Testosterone, Free, Bio/Total (LC/MS/MS) Code: 14966X
4 ------- DHEAs
5 ------- Comprehensive Metabolic Panel w/EGFR
6 ------- CBC w/ diff/PLT
7 ------- Lipid profile
8 605 T3, Total
19 ------- T4, Total
10 ------- Ultrasensitive TSH
12 0.33 Prostatic Specific Antigen (PSA)
----------------------------------------OTHER RESULTS NOT LISTED ON THE ABOVE FORM
4.8 WBC
14.3 HGB
44.0 HCT
33.5 MCH
32.4 MCHC
13.0 RDW
8 MONOCYTES
2 EOSINOPHILS

Age: 55

Height: 5'8"

Weight: 153

Waist size: 30

Neck size: 15.5

Have you lost weight in the past 6 month? If yes, how many pounds? nope

Have you gained weight in past 6 months? If yes, how many pounds? YES 5-7

Has your body tone changed in the past 6 months (harder, softer)? YES, HARDER

When was your last complete physical examination? 1 month past

What were the results of that exam? Overall good, w/ dx of Low T

(FOR OVER 40) Did you have your prostate examined by digital rectal exam? YES

(FOR OVER 40) Did you have your PSA checked? YES

If so, what was it? Methodology was Advia Centaur Chemiluminescent Immunoassay Total: 0.33

Are you taking testosterone now?
YES , IM 100 Bitest
If answer to above question is NO, have you taken testosterone in the past? How long and when did you last stop?

Do you urinate alright?
NO
How many times do you get up at night to urinate ?
0
Does it hurt when you urinate?
NO
Is there any blood in your urine?
NO
Have you had prostatitis (prostate/urinary infections) in the past?
YES, but only when married, frequent UTI
Describe any acne history:
NO
Do you have cold intolerance?
YES
Do you bruise easily?
YES, VERY
Do you have:

Depression
possinbly, SLIGHT
Anxiety YES

Decreased sexual potency (erection quality). If so, is this causing stress in your relationship?
YES, poor erections, no relationship at this time, but still causes anxiety when it comes to have sex
Decreased sex drive
50/50....I still want to have sex, I think about it, but not a physical capability or complete desire
Sleep disturbances
awake every night @ 3 am wide awake for an hour then fall back asleep
Generalized muscle aches and pains
no
Joint pain
NO
Fatigue
NO
Lethargy
SOMETIMES
Sensitive or swollen nipples?
NO
Did you have swollen or painful nipples BEFORE you ever used steroids (for men who have used anabolics AAS)?
NO
Can you feel any lumps around your nipples?
NO
Are you losing your hair?
NOTICING MORE HAIR IN THE SINK RECENTLY
Have you ever taken Propecia or Proscar (finasteride) for hair loss or prostate inflammation?
NO
Were you losing it before you started using steroids (AAS only)? If so, is it falling out more quickly now?
OFF AND ON

Have you had:

Loss of appetite
NO
Unexplained weight loss or weight gain ? which ?
GAIN
Do you consider yourself to be in good health?
YES
Do you sleep well?
NOT REGULARLY
Average hours of sleep per night:
8-9
Do you regularly self examine your testicles?

YES
Tell us about your diet (The more details, the better)
Very good diet, about 4 meals a day, healthy mix of fruits, grains, meat, proteins

Do you exercise? If yes, what type and how frequently?
at least 4 xs a week, mostly hi intensity interval training, TRX, getting back into swimming

Do you feel that you procrastinate a lot and do not have enough mental focus to finish projects?
yes
Are you experiencing a lot of stress lately? For how long and why, DEFINITLY, I HAVE HAD A FAIRLY STRESSFUL LAST COUPLE OF YEARS DUE TO BUSINSESS CIRCUMSTANCES and THE POOR ECONOMY.

 

[robs2nd75]

Had my scan and it came out normal. My Endo feels that I may have Familial hypocalciuric hypercalcemia. Does anyone have any experience/knowledge regarding this disorder?