Questionnaire for men with low shbg on TRT.

Gus80

Member
I want to thank everybody on the forum who wrote about low shbg and TRT.

I read several posts and now I would like to suggest a sequence with data from each user who is willing to share it, so that it is compiled and we can use it as a base.

So I would like to hear from everyone who has low SHBG and is on TRT:

With what weekly dose of testosterone did you feel better?

Applying how many times a week?

Which ester felt better, cypionate, enanthate, propionate, cream, gel, undecanoate, sustanon?

Have you tried using clomid and/or hcg as hormone replacement to raise shbg?

What is the optimal level of Free Testosterone, SHBG and E2 for you?

Any other strategies that helped you increase SHBG, such as: keto diet, carnivore diet, liver medications, diabetes medications, etc?

Have you performed any genetic testing for the following mutations: mthfr, comt, maoa?

Do you have any of these diagnosed disorders: diabetes, insulin resistance/high insulin, fatty liver, metabolic syndrome, overweight/obesity, sleep apnea or other sleep disorders, high homocysteine?

Tanks!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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