Question about t3 and t4

[MNguy]

If t3 is the active thyroid hormone, then what would be the point of even taking t4? I ask because I have been on t3 only treatment since beginning HRT due to high RT3. Wondering if I could benefit from adding in a little t4 to my protocol. T4 is usually at the bottom end of normal or just slightly low on labs. As always, any insight is much appreciated!

 

[Vtail]

I had the same question. My doctors answer was that there may be something else that T4 does that is beneficial, so may as well keep it within the normal range.

 

[Gman86]

There is a possibility that T4 does something beneficial that T3 doesn’t. But most likely the main benefit is just that T4 is like a reserve to pull from when it’s needed. T3 is fast acting and gets used up quick, and if it’s used up and the body needs more thyroid hormone, it’s beneficial to have a constant reserve to always be able to pull from, that the body can then convert to T3 as needed

It might be similar to how low SHBG men seem to have more problems thatn moderate to high SHBG men do. SHBG acts as a time release for the testosterone in ur system. So men that have a healthy supply of test for longer periods of time tend to do better than men with low SHBG levels and the test in their system doesn’t stick around as long and gets used up quicker.

 

[Vince]

I also ask that question, a while back. Here's the thread.

can cytomel by itself be used to treat hypothyroidism - Excel Male TRT Forum

I'm just wondering if anyone uses just Cytomel (Liothyronine) to treat their hypothyroidism?

www.excelmale.com

 

[HealthConscious]

Search youtube for Dr. Ken Berry with thyroid. I've seen 2 or 3 good ones by him including options to the synthetic T4, and the blood work parameters needed for a good diagnosis. T3 can be off due to issues in the gut or liver also.