Question about free t-3

Tonyp56

Member
Long story short I've had lots of ups and downs on TRT. June 17 2017 went to universal men's clinic in Tulsa Oklahoma, that lasted a year of crashed e-2 etc. (I have Post on board). Went to defy back in July of last year. Anyways I've been battling high e-2, (63 first 3 months, then 67 4 months later.) High hemocrits, blah. Still feel fatigue and not energetic but it comes in cycles. (Current protocol is 500 iu of hcg twice week, 40 mg or testosterone cyp every other day and .125mg of anastrozole every other day. So on Feburary 4th at last appointment was told we need to have limited labs (total t, free t, e-2, cbc, and free t-3 to make sure thyroid was not causing issues) in 3 months. Initial blood work for Defy had tsh of 2.4xx, so 3 months later they checked everything again along with free t3 and t4, and reverse t3, at that time my t3 was 4.3, and was told everything looked good/great.

Anyways I did blood donation (3-4-2019 because of hemocrits etc.first time I've done one with defy, universal men's clinic had me do it 4 times in 1 year! So put off as long as i could. It did make me feel better but fatigue, sexual function still no change) and had to do cbc followup 2 weeks later. Decided to do free t3 and cbc at same time so be little less here in about 6 weeks (whenever 3 months ends up being) for followup labs. Tuesday of this week (3-19) went in for blood test and I was fasting.

Anyways my free t3 came back at 4.7 (range given is 2.0-4.4). Any ideas why or what is causing? Called defy and basically told to pay for another consult. I don't have the money. Thinking of going to a real doctor that I can use insurance with. I don't have another $90 mid level or $160 for Dr, or even $45 for nurse, need to order more meds and don't really have that money either. But I'm curious what others think. No not asking for medical advice, I'm looking for opinions so I can know what to expect. Thanks and sorry so long. If more info is needed I'll gladly five.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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