PSA Levels and TRT

raygo

New Member
I had all my blood work anticipating starting TRT through the Body Logic chain. My results came back with elevated PSA (3.1 on the 0-4 range). While not over 4, my doc (actually the Body Logic doc, not my Primary Care doc) wants me to see a specialist to screen for prostate irregularities before starting. Haven't done anything yet. This barrier is bumming me out. What are the real issues with TRT and the prostate? Has anyone encountered this roadblock before? I haven't found too many hits when searching. My age is 55, so I imagine my PSA should probably be btw 2 and 3 for my age? Also, my research did reveal that sex (i.e. ejaculation) and use of ED drugs or herbs can raise the PSA level. No one told me this. It seems like the instructions for blood work should include this information.
 
It's common and the Doctor is doing the correct procedures to rule out any chance of Prostate cancer.

Prostate cancer is androgen dependent so any increase in Testosterone serum levels would be like pouring gas on a burning fire.

Rule out any possibility of cancer and you'll be good to go...and have peace of mind as well.

You are also correct that PSA can be elevated 24 hours after ejaculation so no sex or fooling around for at least 24 hours...I usually go 48 to get a correct reading.

Your Doc should have told you this especially screening for TRT; but now you know.

Get your prostate checked out, at your age and slightly elevated levels, it just good to know.
 
One of the most common reasons for PSA elevations is prostatic infections. In these cases, PSA decreases after antibiotics. But treating prostatitis can be challenging in some.

One of my clients sent me this list that a lab told him to avoid before getting a PSA test (don't laugh):
Fasting for 8-12 hours
No alcohol for 72 hours
No ejaculation for 48 hours
No horse riding for 2 days
No bicycle or motorcycle riding for 2 days
No exercising for 2 days
No suppositories for 3 days
No urethral procedures for 3 days
No anal touching for 3 days
No cystoscopy for 5 days
No transrectal ultra sound for 7 days
No colonoscopy for 15 days
No dynamic urine study for 21 days
No prostate biopsy for 30 days
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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