Protecting Muscle During Hospitalization: Protein, Activity & Prehab

madman

Super Moderator

In this Mini Mikkipedia episode, Mikki dives into new research from Dr. Fuchs and Professor Luc van Loon on the critical role of protein and activity in preserving muscle during hospitalization. She explains just how quickly muscle mass can decline with bed rest or critical illness, why standard hospital meals fall short nutritionally, and how inadequate protein and energy intake accelerate muscle loss. Mikki outlines practical strategies—from protein targets and essential amino acids to simple activity or electrical stimulation—to help mitigate muscle wasting. She also highlights the importance of “prehabilitation” before elective surgery. Whether you’re an athlete, a caregiver, or someone preparing for surgery, this episode offers valuable insights on protecting strength when it matters most.




Episode Highlights:

  • Why muscle loss in hospital can reach 3% per day in ICU patients
  • The role of protein intake (1.2–1.5 g/kg+) in slowing muscle atrophy
  • How energy balance influences anabolic resistance and recovery
  • Practical strategies: protein powders, amino acids, and even bedside activity
  • The case for prehabilitation before elective surgery
 

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Predict estradiol, DHT, and free testosterone levels based on total testosterone

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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