Post First TRT injection need advice

LowT2014

Member
Hi all

Did my first TRT with Reandron 1000 which is Test-Undeconate(Same as AVID or Nebido but it is called Readron in Australia) 4ml in glutes got sick almost 6 hrs after it with flu like symptoms, fevers and chills that went away after 2 days but my muscles were full from next day onwards, and my gonads turned immediately soft within 6-8 hrs as well.

For some reason my gonads back to full the way they were before at least 85%. Also notices muscle fullness diminished and now I got headaches not sure if its related or not. Its been 5 days today in total so far. (headaches only started today)

My Lab work is due in 3 weeks now, what is the normal E2 levels for guys so I know what to tell my doctor if I need AI etc. please give me a reference page or link so I take a print out to my normal GP as my Endocrinologist appointment is 13 weeks away as he wants me to have TU administered at 6 weeks and new blood panel done on 11th week so he can check my levels and adjust dosage as needed not even sure if I go with TU or TE at this stage.

Cheers
 
Last edited:
When men start TRT, their testicles get bigger (back to where they use to be when their T was normal in the past) during the first few weeks. Some remain with this improvement and some do not.

An estradiol blood level (tested by ultrasensitive LC/LMC test) should be under 50 pg/ml. Most men do not need anastrozole, by the way.

The headache you have may be caused by other reasons or by higher blood pressure caused by TRT in some men.

How to Print Factsheets for Your Doctor from ExcelMale.com
Role of Estradiol in Men and Its Management
 
When men start TRT, their testicles get bigger (back to where they use to be when their T was normal in the past) during the first few weeks. Some remain with this improvement and some do not.

An estradiol blood level (tested by ultrasensitive LC/LMC test) should be under 50 pg/ml. Most men do not need anastrozole, by the way.

The headache you have may be caused by other reasons or by higher blood pressure caused by TRT in some men.

How to Print Factsheets for Your Doctor from ExcelMale.com


Role of Estradiol in Men and Its Management


Thanks for the reply Nigel appreciate it, will keep an eye on E2 and post new lab results when I get them.

Cheers
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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