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jabarnes2006

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T levels are double what they were when I first started but my Estrogen is way up to...What should I do to help stop this?
 

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Do you have a reference range for estradiol from this lab? What protocol are you on? How many days after last injection were these labs drawn?
 
This is all I got from the doc this morning so Im not sure what range they use. I took my injection a week before the lab which to be honest Im very surprised by the result because I timed the test of 7 days after because thats when I notice the drop of energy
 
Sounds like you got the timing right, right before you were due your next injection. On your E2 if you can find out if its the standard test or the sensitive test by my god 128 is high no matter what.
 
This is all I got from the doc this morning so Im not sure what range they use. I took my injection a week before the lab which to be honest Im very surprised by the result because I timed the test of 7 days after because thats when I notice the drop of energy

What protocol are you on?
 
Ask your doc if estradiol test used liquid chromatography/ mass spectrometry or immuno assay. If it was the later, your value is over estimated.

What is your T dose and frequency?
 
They gave me estradiol and have me doing sub q injections of .75 ml twice a week. He said it would be hard for me to feel anything different with the levels being that high.
 
If the code from your results is a labcorp test it is a sensitive, not ultra-sensitive and is immuno-assay based and as Nelson points out over stated for a male
 
.75 ml twice a week is 300 mg a week which is a high dose in TRT replacement for men.

The default estrogen lab designed for women tends to over estimate values for men but even still, you are elevated for sure and need to get the "Sensitive" estrogen lab quickly so it can be determined how much of an AI you will need to get this value to a healthy level...being high like this is not healthy and can have some nasty side effects as well.

You are missing just about every lab necessary to manage your health under TRT.

These are the labs your Physician should have run:

Testosterone Total
Testosterone Bioavailable
Testosterone Free
SHBG
DHT
DHEA-S
Estradiol (“sensitive” assay only)
PSA
Prolactin (if T <150, or if sexual dysfunction even after proper TRT)

I suspect your Physician is not trained in proper TRT management in men or he would have ordered these labs.
 
.75 ml twice a week is 300 mg a week which is a high dose in TRT replacement for men.

The default estrogen lab designed for women tends to over estimate values for men but even still, you are elevated for sure and need to get the "Sensitive" estrogen lab quickly so it can be determined how much of an AI you will need to get this value to a healthy level...being high like this is not healthy and can have some nasty side effects as well.

You are missing just about every lab necessary to manage your health under TRT.

These are the labs your Physician should have run:

Testosterone Total
Testosterone Bioavailable
Testosterone Free
SHBG
DHT
DHEA-S
Estradiol (“sensitive” assay only)
PSA
Prolactin (if T <150, or if sexual dysfunction even after proper TRT)

I suspect your Physician is not trained in proper TRT management in men or he would have ordered these labs.


All of this.
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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