New bloods have come any , anything thoughts pls ?

[Scottmcty]

Hi guys


My new bloods have come in any thoughts on these , I’m pretty happy with what’s come back

My estrogen looks a little high or is this ok with my test levels ?


Some imput would be good thanks


Daily injections 20mg , 140 mg total a week

Take all my daily vitimins and mins

5 mg of cialias daily



Thanks

 

[Scottmcty]

Ps my prolactin looks very high , could this be as estrogen a little high maybe ?

 

[WhiteMale]

Oestradiol is not the test you should be getting.

UltraSensitive LC/MS/MS is what you should be getting.

 

[Scottmcty]

I’m in uk , that’s all we have here I’m afraid .

 

[madman]

Hi guys


My new bloods have come in any thoughts on these , I’m pretty happy with what’s come back

My estrogen looks a little high or is this ok with my test levels ?


Some imput would be good thanks


Daily injections 20mg , 140 mg total a week

Take all my daily vitimins and mins

5 mg of cialias daily



Thanks

How long have you been on this protocol and how do you feel overall?

Need a more thorough set of labs as you are missing the most critical blood marker free testosterone.

TT is important to know but FT is what truly matters as its the active unbound fraction of T responsible for the positive effects.

In order to know where your FT truly sits you would need to have it tested using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG (low/high).

If you do not have access to such which is most likely the case seeing as you liven the UK then you will need to use/rely on the next best testing method the go to linear law-of-mass action Vermeulen (cFTV) which will give a good approximation.

Also missing critical blood markers RBCs, hemoglobin, hematocrit and iron/ferritin.

Need a full thyroid panel too.

As you can see on a daily injection protocol 20 mg T (140 mg/week) you are hitting a robust TT 674.9 ng/dL (23.4 nmol/L) but it means nothing when looking at the bigger picture here without knowing where the most critical fraction FT sits.

We can easily calculate your FT using the cFTV seeing as you had your SHBG tested.

The calculator is available online for free to the general public.

With a robust TT 674.9 nmol/L, lowish SHBG 16 nmol/L and Albumin 4.3 g/dL (default) your high-end cFTV 20.7 ng/dL would be a healthy.

Free & Bioavailable Testosterone calculator

Even though your TT is far from high with a lowish SHBG 16 nmol/L your FT is still high-end.

Men with low or lowish SHBG do not need to hit a high TT in order to achieve a healthy/high FT.

Would not get too caught up on your high estradiol if you feel well overall.

If you have elevated CRP or you were one of those poor bastards who crushed their estradiol from overusing an aromatase inhibitor (AI) then you’d want the most accurate assay available LC-MS/MS, or better yet a CDC-standardized LC-MS/MS assay (US).

Otherwise the standard immunoassay is usually sufficient.

Your prolactin is just over the upper limit but I would not be too concerned unless you were experiencing sides.

 

[Scottmcty]

Will add more bare with me


Been on this for 4 weeks now

Was on 120 weekly but didn’t feel very good tbh

 

[Scottmcty]

Just added my full bloods , I thought I uploaded them

My ferritin is low as gave blood abut 4 to 5 weeks before bloods

But doctors thinking of putting me
On iron tablets

 

[Scottmcty]

More bloods

 

[Scottmcty]

.

 

[Scottmcty]

.

 

[Scottmcty]

.

 

[Scottmcty]

.

 

[Scottmcty]

.

 

[Scottmcty]

.

 

[Scottmcty]

.

 

[Scottmcty]

How long have you been on this protocol and how do you feel overall?

Need a more thorough set of labs as you are missing the most critical blood marker free testosterone.

TT is important to know but FT is what truly matters as its the active unbound fraction of T responsible for the positive effects.

In order to know where your FT truly sits you would need to have it tested using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG (low/high).

If you do not have access to such which is most likely the case seeing as you liven the UK then you will need to use/rely on the next best testing method the go to linear law-of-mass action Vermeulen (cFTV) which will give a good approximation.

Also missing critical blood markers RBCs, hemoglobin, hematocrit and iron/ferritin.

Need a full thyroid panel too.

As you can see on a daily injection protocol 20 mg T (140 mg/week) you are hitting a robust TT 674.9 ng/dL (23.4 nmol/L) but it means nothing when looking at the bigger picture here without knowing where the most critical fraction FT sits.

We can easily calculate your FT using the cFTV seeing as you had your SHBG tested.

The calculator is available online for free to the general public.

With a robust TT 674.9 nmol/L, lowish SHBG 16 nmol/L and Albumin 4.3 g/dL (default) your high-end cFTV 20.7 ng/dL would be a healthy.

Free & Bioavailable Testosterone calculator

View attachment 57859
View attachment 57858

Even though your TT is far from high with a lowish SHBG 16 nmol/L your FT is still high-end.

Men with low or lowish SHBG do not need to hit a high TT in order to achieve a healthy/high FT.

Would not get too caught up on your high estradiol if you feel well overall.

If you have elevated CRP or you were one of those poor bastards who crushed their estradiol from overusing an aromatase inhibitor (AI) then you’d want the most accurate assay available LC-MS/MS, or better yet a CDC-standardized LC-MS/MS assay (US).

Otherwise the standard immunoassay is usually sufficient.

Your prolactin is just over the upper limit but I would not be too concerned unless you were experiencing sides.

Thanks for the reply

I feel ok , still early days on this protocol

Libido is not the best

When I moved from 120 mg to 140

I started feeling better and libido was good then it started dropping off ?

Maybe the e2 and prolactin rising ?

 

[Scottmcty]

How long have you been on this protocol and how do you feel overall?

Need a more thorough set of labs as you are missing the most critical blood marker free testosterone.

TT is important to know but FT is what truly matters as its the active unbound fraction of T responsible for the positive effects.

In order to know where your FT truly sits you would need to have it tested using the most accurate assay the gold standard Equilibrium Dialysis especially in cases of altered SHBG (low/high).

If you do not have access to such which is most likely the case seeing as you liven the UK then you will need to use/rely on the next best testing method the go to linear law-of-mass action Vermeulen (cFTV) which will give a good approximation.

Also missing critical blood markers RBCs, hemoglobin, hematocrit and iron/ferritin.

Need a full thyroid panel too.

As you can see on a daily injection protocol 20 mg T (140 mg/week) you are hitting a robust TT 674.9 ng/dL (23.4 nmol/L) but it means nothing when looking at the bigger picture here without knowing where the most critical fraction FT sits.

We can easily calculate your FT using the cFTV seeing as you had your SHBG tested.

The calculator is available online for free to the general public.

With a robust TT 674.9 nmol/L, lowish SHBG 16 nmol/L and Albumin 4.3 g/dL (default) your high-end cFTV 20.7 ng/dL would be a healthy.

Free & Bioavailable Testosterone calculator

View attachment 57859
View attachment 57858

Even though your TT is far from high with a lowish SHBG 16 nmol/L your FT is still high-end.

Men with low or lowish SHBG do not need to hit a high TT in order to achieve a healthy/high FT.

Would not get too caught up on your high estradiol if you feel well overall.

If you have elevated CRP or you were one of those poor bastards who crushed their estradiol from overusing an aromatase inhibitor (AI) then you’d want the most accurate assay available LC-MS/MS, or better yet a CDC-standardized LC-MS/MS assay (US).

Otherwise the standard immunoassay is usually sufficient.

Your prolactin is just over the upper limit but I would not be too concerned unless you were experiencing sides.

Is my low shbg a problem is this as doing daily injections ?


My multivitamin has boron in it , this might of lowered it a tad , should I do anything about this ?


I’ve uploaded some more blood results , sorry if they are all over the place

 

[madman]

Just added my full bloods , I thought I uploaded them

My ferritin is low as gave blood abut 4 to 5 weeks before bloods

But doctors thinking of putting me
On iron tablets

4 weeks is not long enough to assess your protocol as you upped your dose of T 120-140 mg/week and it will take 4-6 weeks TC/TE for blood levels to stabilize so your hormones would be in flux leading up until steady-state is achieved and it is common to experience ups/down along the way as the body is trying to adjust.

For most there when starting therapy or tweaking a protocol there will be a short-lived honeymoon period where one can feel euphoric and experience an increase in libido and erections (spontaneous/nocturnal) but this is short-lived and things will tend to wane back to the norm as the body adapts.

The first 4-6 weeks mean nothing when looking at the big picture here because once steady-state is achieved it will still take the body a few more months to adapt to its new set-point and this is the critical time period when one needs to gauge how they truly feel overall regarding relief/improvement of low-T symptoms.

Need to tread lightly on donating blood and it is critical to make sure you do not crash your ferritin/iron otherwise you will open up a can of worms and run into issues.

Any dysfunction thyroid can male or break the effectiveness of T therapy.

 

[madman]

Thanks for the reply

I feel ok , still early days on this protocol

Libido is not the best

When I moved from 120 mg to 140

I started feeling better and libido was good then it started dropping off ?

Maybe the e2 and prolactin rising ?

Hard to pinpoint here as you are only 4 weeks in.

Keep in mind the honeymoon period is short-lived.

 

[Scottmcty]

So keep on this and re test again in another 4 to 6 weeks ?