Need to increase E2 (temporarily)

My protocol is 200mg/week Test Cyp (100mg E3.5D) that is pre-mixed with 1mg of Arimidex (0.5mg E3.5D) and 500iu of HCG E3.5D.

My E2 before treatment was 55 (non sensitive). That's why the Dr added the AI from the beginning.

After a couple of weeks I was feeling like my E2 was low, so I did my own tests:
5/1 PEAK 14 pg/mL
5/18 TROUGH 15.8 pg/mL

My Dr is going to lower the Arimidex by half, but I cannot get the refill for another few weeks, and I don't want to continue feeling this way until then.

So what can I take (supplement) to increase my E2 until then?

DHEA? (how much)
More HCG? (how much)
I've read about DIM and Calcium d-Glucarate, but I can't determine if they increase or decrease E2.

I would really appreciate any advice on how to increase E2!!!
 
Last edited:
Calcium d-GlucarateMy protocol is 200mg/week Test Cyp (100mg E3.5D) that is pre-mixed with 1mg of Arimidex (0.5mg E3.5D) and 500iu of HCG E3.5D.

My E2 before treatment was 55 (non sensitive). That's why the Dr added the AI from the beginning.

After a couple of weeks I was feeling like my E2 was low, so I did my own tests:
5/1 PEAK 14 pg/mL
5/18 TROUGH 15.8 pg/mL

My Dr is going to lower the Arimidex by half, but I cannot get the refill for another few weeks, and I don't want to continue feeling this way until then.

So what can I take (supplement) to increase my E2 until then?

DHEA? (how much)
More HCG? (how much)
I've read about DIM and Calcium d-Glucarate, but I can't determine if they increase or decrease E2.

I would really appreciate any advice on how to increase E2!!!

Don't inject anymore of that T. Wait for a new bottle. Why won't he give you clean T cyp and a seperate AI?

A reduction in your T lvl will be less painful than crashing your E2 IMO.

No Calcium d-Glucarate or DIM
50mg DHEA/day
1000IU HCG /wk divid it up how ever you like 2 500s, 4 250's
 
There in lies the problem with compounding like that you have no adjustment possibility.

If you need some E while you go thruough that the best thing I know of is to go to WalMart and buy the cheap DHEA tablets...should get some aromatase as it passes thru the liver, just go easy on it and stay under 25mg if not less.
 
There in lies the problem with compounding like that you have no adjustment possibility.

If you need some E while you go thruough that the best thing I know of is to go to WalMart and buy the cheap DHEA tablets...should get some aromatase as it passes thru the liver, just go easy on it and stay under 25mg if not less.
Thanks Vince...micronized or just the regular DHEA?
 
What about Soy? I've read that people with high E2 should stay away from Soy...so that would indicate that the converse should apply (increase low E2). I've bumped up my daily HCG to 200iu.

Getting trough bloods tomorrow morning.
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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