Natesto nasal spray - Any thoughts on this?

CSI007

Member
When I first visited a urologist he gave me a sample of this. I didn't want to take it until I investigated my options further. It still sits in the drawer almost a year later.

Anyway,
The company that was going to distribute it in the US dropped out earlier this year but it looks like another company has picked up distribution of the product.

You have to spray the gel into your nose three times per day to keep a steady stream of T I guess in your body.

In case my increase of HCG monotherapy dosage does not work, I want to have all possible options on the table when/if the time comes to move on to TRT.

I think I would be leaning towards compounded cream first, then injections but this might be an alternative too if the cost is not prohibitive.

My only real concern is having the T go into the body so close to the brain..Doesn't look like there is much research on the subject.
 
I found that thread after I made my post. One person impressed another not so much.

It looks like it will be cost prohibitive anyway @ 250 per container. Looks like they will give you a huge discount for the first 25 though. After that they got you hooked right?
 
I would try the topical T first for 5-6 weeks and see how you feel. If you do not absorb it well then move to T shots twice weekly.
 
I got sinus congestion and a light headache. As you can see in the link above, the peaks are high after application. I did not like the feeling.
 

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Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

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Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

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The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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