Nashtide's latest labs...

Both my MD's keep my DHEA well above range and I also feel good on it. Dr.Crisler mandates 800mg daily of magnesium and he claims that helps to keep E2 under control. I used to have to take a lot of arimidex and then I started taking 600mg magnesium and now I'm down to .125mg arimidex twice a week.

Mag is not going to control E2 I'd like to read that myself. I know he's stated 800mg for blood pressure though but if mag controls E that's a new one.
 
Your AI dose is so miniscule I can't imagine that would swing you one way or the other but in that same regard would be easy to eliminate it entirely and see how it goes, I think your E2 being closer to your SHBG might a good thing, perhaps. Something I'm working on.
Interesting. I've never heard the E2 and SHBG being the same level as a goal. I'd also like more info on magnesium and blood pressure.
 
So, based on labs and suggestions from the peanut gallery, I decided to stop taking the AI 3 weeks ago. I was taking a very small dose and my E2 ultra sensitive was 25. So far I don't feel any different. I don't know if I was actually expecting to feel anything. Hopefully no news is good news.
 
Both my MD's keep my DHEA well above range and I also feel good on it. Dr.Crisler mandates 800mg daily of magnesium and he claims that helps to keep E2 under control. I used to have to take a lot of arimidex and then I started taking 600mg magnesium and now I'm down to .125mg arimidex twice a week.

What form of magnesium do you take?

I take ~3,600 MG of Magnesium Citrate, which is ~540 MG of elemental magnesium.


But I also take 666 mg of Magtein (magnesium l-threonate) which is 48 mg of MG, sometimes I take double that. Magnesium l-threonate is the only form of magnesium supplement that can cross the blood/brain barrier.

My E2 is fairly low, though it does follow testosterone up so when my TT is above range my E2 is also above range. However, the ratio of TT/E2 stays high. I didn’t think it had anything to do with MG, but maybe it does.
 

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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