Nandrolone decanoate relieves joint pain in hypogonadal men: a novel prospective pilot study and review of the literature
For decades, testosterone has been the sole instrument
in the andrologist’s arsenal for the ongoing treatment
and management of male hypogonadism. However, with
increased interest and emerging research, there now exist
more options than ever to help combat the sequelae of this
devastating clinical condition. Nandrolone is a particularly
compelling medication that has significant beneficial effects
on joint pain in hypogonadal men, reducing their reliance
on chronic pain medication and reducing pain scores in
responding men by more than half. Although further studies
are required to replicate and characterize these findings on a
larger scale, they suggest a novel indication for a fascinating
drug that appears to hold great promise for future clinical
use. It is increasingly apparent that the field of modern
andrology is evolving rapidly with ever-expanding options
to assist our patients in novel and exciting ways.
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