My first labs

Jntsrgn

Member
A bit confused by these results. I think I was being mistreated on BioTE pellets and have converted to T-cyp 40mg IM M-W-F and HCG 500 IU T-Th-Sat.

Total test: 928
Free test: 12
Estradiol sensitive: 5.9
SHBG: 78
DHEA: 574

Why so low on the free testosterone? What to do about the SHBG?
 
Wow.
I personally haven't seen a Total that high with such a low Free.
Only way to overcome that super high SHBG is to increase the dose.
You're gonna be running a fairly high total, but that's what's needed to push that SHBG down and drive that FreeT up.

No AI?
That's non-existent estrogen.
 
I'd cut that way back if not remove completely.

Out of curiousity, do you have any thyroid numbers?
Would like to see what that's doing as well.
 
SHBG is astronomical, as Sean says you need to up the dose, your TT is probably going to have to be 1000+, 1100, or even 1200 to get Free T to come up.

I think that 1mg of Anastrozole is too much but too little info is present here to give an informed opinion, like when the blood draw occurred or if problems are present related to low (or high) Estrogen.
 
Wow.
I personally haven't seen a Total that high with such a low Free.
Only way to overcome that super high SHBG is to increase the dose.
You're gonna be running a fairly high total, but that's what's needed to push that SHBG down and drive that FreeT up.

No AI?
A bit confused by these results. I think I was being mistreated on BioTE pellets and have converted to T-cyp 40mg IM M-W-F and HCG 500 IU T-Th-Sat.

Total test: 928
Free test: 12
Estradiol sensitive: 5.9
SHBG: 78
DHEA: 574

Why so low on the free testosterone? What to do about the SHBG?
I have to run 1200 plus on my TT for get my FT around 30. IMO your E is way to low and might consider not using an AI.
 
Short of a liver transplant, you'll need to throw more testosterone at the insanely high SHBG. You're going to need a Total T of 1500> to get Free T where it needs to be.



Are you kidding me......again.....really?

What is it you have a hard time understanding regarding the newer research on SHBG:T binding?




An extremely high TT is not needed even with one having high SHBG. With a TT of 928 ng/dL, SHGB 78 nmol/L and Albumin 4.3 g/dL (mean) his FT using the newer calculated TruT method.....TruT Free Testosterone Calculator by FPT.....(which everyone should be using) is 27.71 ng/dL (above the mean 23.5 ng/dL of the reference range 16-31 ng/dL).
Screenshot (395).webp



With a TT 928 ng/dL his FT levels are by no means low......let alone sub-par even with an SHBG of 78 nmol/L.




Sure he has room to easily bring his FT levels up higher (top of the reference range or above).....and if anything he would only need to hit a TT of 1000 ng/dl to have his FT at 30.39 ng/dL (top of the reference range) or hit a TT 1200 ng/dL to have his FT at 37.89 ng/dL (over the top of the reference range).
Screenshot (391).webp





Screenshot (396).webp





Telling the man he would need a TT of 1500 would have his FT absurdly high 49.25 ng/dL
Screenshot (394).webp
 

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Nothing you can do about shbg. It may drop some over time with trt.

Ignore your free T test. That number is garbage.
I was on BioTE pellets for the last year with a total T of 1600. I hated getting the pellets and I fluctuated wildly with how I felt.
Are you kidding me......again.....really?

What is it you have a hard time understanding regarding the newer research on SHBG:T binding?




An extremely high TT is not needed even with one having high SHBG. With a TT of 928 ng/dL, SHGB 78 nmol/L and Albumin 4.3 g/dL (mean) his FT using the newer calculated TruT method.....TruT Free Testosterone Calculator by FPT.....(which everyone should be using) is 27.71 ng/dL (above the mean 23.5 ng/dL of the reference range 16-31 ng/dL).
View attachment 7880


With a TT 928 ng/dL his FT levels are by no means low......let alone sub-par even with an SHBG of 78 nmol/L.




Sure he has room to easily bring his FT levels up higher (top of the reference range or above).....and if anything he would only need to hit a TT of 1000 ng/dl to have his FT at 30.39 ng/dL (top of the reference range) or hit a TT 1200 ng/dL to have his FT at 37.89 ng/dL (over the top of the reference range).
View attachment 7881




View attachment 7882




Telling the man he would need a TT of 1500 would have his FT absurdly high 49.25 ng/dL
View attachment 7878
Thank you for the information. My albumin was 4.6
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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