My first blood test, share your thoughts please :)

pakman

New Member
Hi guys,

these are bits from my first blood work after about 8 weeks on trt. I inject test e, 100ml every 4 days.

ESTRADIOL E2 220.3 pmol/l (28-156 pmol/l)

TESTOSTERONE TST 41.66 ↑ nmol/l (7.57-31.4)

DHEA-s 315.3 ug/dl (70-492)

FREE TESTOSTERONE 30 ng/l (8,8 - 27)

FT3 4.59 pmol/l (3.13-6.76)

FT4 19.26 pmol/l (12.0-22.0)

TSH 1.85 mIU/l (0.27-4.20)

LH<0.1 mIU/ml (1.7- 8.6 mIU/ml)

HDL CHOLESTEROL 43 mg/dl (>40)

TRIGLICERYDY 49 mg/dl (<150)

CHOLESTEROL CA&#321;K. 158 mg/dl (<200)

LDL CHOLESTEROL 105 mg/dl (<130)


please share your thoughts and ignore spelling mistakes (copy and paste from different language)


Got a question, I started to feel absolutely great after like 17 days after starting injections. However that feeling is gone:( I sleep better, I'm less tired, however I started to feel depressed again;/ do you guys think it might be due to elevated E2?
 
pakman:

Was estradiol measured using the ultrasensitive test? In general your numbers are not bad at all. What else besides TRT are you taking? Height and weight?

Mood is not only linked with hormones, by the way. There are factors like sleep quality, stress/coping issues, low dopamine and/or serotonin, etc that can cause low mood beyond what may be caused by low T or thyroid.
 
Hi Nelson, thank you for your reply.

I'm on testosterone only. Apart from that multivitamins, good diet (almost no junk food), gym goer, no alcohol, no cigarettes or other drugs. My sleep has improved significantly since starting trt, however due to shift work (days/nights) my sleep pattern is not that great. I felt absolutely awesome 3 weeks into trt, now mood is ok-ish, I feel like tired (not like before trt however). Another thing I noticed is that I had morning wood every single day, it's not the case nowadays (no erectile dysfunction though). I got myself tamoxifen, should I give it a try?
 
method 'ECLIA System Cobas e' if that tells you anything Nelson? They did not know what 'ultra-sensitive' method is, direct translation did not work :)
 
Sensitive assay or not, your Estrogen levels are far over the reference range and this can cause all types of negative side effects like feeling fatigued, low/no libido, erection problems, sore joints and many more.

The symptoms you describe are correlated to elevated Estrogen levels as well.

You need to either reduce your Testosterone dose or discuss using a lose dose aromatase inhibitor as part of your protocol because this won't go away on its own.

Go to the forums and read about Testosterone side effects and educate yourself my friend!
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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