mTOR, Muscle Building pathway or cancer pathway?

Will Brink

Member
Truth is, it appears to be both. Per usual, too much appears a negative, too little, also a negative
Supplement companies are constantly pushing mTOR as the magic pathway to building muscle, and various net guru type talk about keeping mTOR activated, with heavy marketing of Leucine, BCAA, etc. to keep mTOR activated. It’s unlikely that keeping an anabolic pathway such as mTOR active is a path to longevity. It’s interesting to note, cancer researchers, anti aging researchers, etc are looking for ways to limit/control mTOR.

Cont:

http://www.brinkzone.com/articles/mtor-muscle-builder-or-cancer-pathway/
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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