Men who are primary and use HCG.

Vince

Super Moderator
Before I started trt I had primary hypogonadism. I did have very low estradiol levels before starting trt and I've never had any estradiol issues, never needing to use an AI. So I'm wondering are all men that are primary like me, never having any issues with estrogen and never needing to use an AI?
 
Before I started trt I had primary hypogonadism. I did have very low estradiol levels before starting trt and I've never had any estradiol issues, never needing to use an AI. So I'm wondering are all men that are primary like me, never having any issues with estrogen and never needing to use an AI?

Men who have had orchiectomy due to testicular cancer become primary, so those in that situation here could give an idea about your question needing to use an AI.
 
Ive considered the angle like this, if youre primary, the problem may not be limited to Testosterone, but also Aromatase, even fertility. Just a blanket covering several of what we know is produced in the testes. Of all my E problems that I have, when I dropped HCG for a month and only used Cyp it didn't alter my E tests one bit. No dramatic decrease in E.
 
It is true, If you are primary and lack the testes, then you lack everything produced on testes (except the amounts produced in adrenal glands), but if you have the testes and are primary, many other things may be also affected to some extension at the testes, starting by sperm production...
For Aromatase: If you have a deficit of Aromatase, you have chances to behave as primary but more likely with normal to high T levels. If you are an over-aromatiser, then you may become primary with high E levels, low T Levels and and very sensitive to have High E when getting even small amounts of exogenous Testosterone. None of these two situations seems ti fit to you.
All I say is only a guess... I am far from being and expert on this matter. Just learning because this problem of Low T has reached me at my late fourties..
 
Before I started trt I had primary hypogonadism. I did have very low estradiol levels before starting trt and I've never had any estradiol issues, never needing to use an AI. So I'm wondering are all men that are primary like me, never having any issues with estrogen and never needing to use an AI?
I have primary hypogonadism and i have normal estrogen level, low testosterone, low sperm count and High LH and FSH. I am starting my TRT+HCG+FSH or TRT+Clomid from next month. Any suggestions?
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
4
Guests online
351
Total visitors
355

Latest posts

Back
Top