Medherant transdermal patch development collaboration with Bayer

madman

Super Moderator


Coventry, UK (25 March 2024): Medherant Limited (“Medherant”) announces that it has entered into a Development Collaboration Agreement with Bayer for the development of a transdermal patch product for delivery of an already-approved oral medicine.

For the last 3 years, Medherant and Bayer have worked on formulation development for this product, utilising Medherant’s expertise in the use of laboratory models for assessment of transdermal drug delivery with the TEPI Patch® technology.


The Development and Collaboration Agreement marks the movement of the collaboration to the next phase of development as Medherant and Bayer move the programme to non-clinical studies and approach technology transfer for patch production at Medherant’s contract manufacturing partner. Medherant is responsible for leading the programme through to completion of the clinical proof of concept study.

Following a successful outcome to the clinical proof of concept study, Medherant and Bayer expect to negotiate a definitive licence agreement to enable Bayer to complete the development programme and pursue commercialisation of this novel TEPI Patch transdermal drug delivery product. Medherant anticipates that the licence agreement will provide for payments to Medherant through the development and registration process as well as royalties payable on sales of this product.

Bayer is committed to transforming self-care by offering precision health solutions to enable consumers to better understand and make informed decisions about their own personal health and lifestyle choices.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

Beyond Testosterone Podcast

Online statistics

Members online
1
Guests online
162
Total visitors
163

Latest posts

Back
Top