Low T, High Prolactin - Thoughts?

Harpua

New Member
50 Y/O with long history of Low T that started in early 30s - did TRT for 4 years but stopped 2 years ago after not noticing any physical benefit. Since last year, worsening (and now flatlined) libido and ED issues along with off and on depression. Was on Welbutrin for a year and weaned off this spring. Just got some labs done on my own and facing a 6 month+ wait to see an Endo:

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Prolactin is elevated but, from reading, not tumor-level elevated (?). That said, I have a feeling high prolactin has been the cause of my severely reduced libido, etc. Wondering if cabergoline will make me feel better but obviously can't self-prescribe. Doubt my PCP will prescribe without Endo.

Any suggestions on other tests to run? CBC, PSA, Lipids normal. BTW, my total T before starting TRT (this is 8 years ago) was 211. I don't have any other prolactin levels since I'm the only one who has ordered it. Appreciate any advice from anyone who has had a similar path....
 
With high prolactin and low libido, your PCP should prescribe prolactin. Show them a medical study about it - that will give them more confidence that it is OK to prescribe it in such cases.
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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