Lost Physical Libido

How much Anastrozole were you taking? Seems like this happens all the time, the E2 crash and continued issues.

I was on 0.25mg 3x per week. Then E crash last September, and have been off since. Switched at that time from T injections 2x to 3x per week. The thought was moving to lower dose, higher frequency would mitigate the need for the A.
 
I was on 0.25mg 3x per week. Then E crash last September, and have been off since. Switched at that time from T injections 2x to 3x per week. The thought was moving to lower dose, higher frequency would mitigate the need for the A.

Lower dose, higher frequency lowered my E2 a bit Every 3 days - I also supplemented with zinc. Mine was 40 and dropped to 35 so not much but a bit. I was told that both numbers were ok.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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