Is My SHBG Too Low/Too High?

Although there are additional factors to consider, I would say it depends quite a bit on your Total T. For example, if your Total T was 300, then I would say "yes" whereas if your Total T was 1000 then likely "no." Chasing a specific number is a good way to go down a rat hole.
 
It is often stated that the ideal FREE Test range is 2% to 3% so it is typically more productive to calculate your Free T than just focusing on a fixed SHBG level. Use this calculator: http://www.issam.ch/freetesto.htm

That said, SHBG that is either too low or too high (above and below reference range) can be problematic.
 
Too high, Id say over about 25-30, and you'll suffer from a lack of Free T, the 2-3% that ERO refers too. Too low SHBG and you'll be driven to having to inject EOD or even daily. That's about the gist of low and high SHBG.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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