Is depression along tiredness normal for a clomid restart after Trt? Almost 6 weeks in i believe. Really hoping for another baby

Gh72686

New Member
questions in bold below for those who want to skip...

Reddit is of no use and ive read through some stuff here but any encouragement or advice would be huge. Me and my wife just turned 37 and im sad we waited so long to try for our second. On trt for 3 and a half years and hcg didnt work. On a 5000 iu a week the labcorp at home test showed 10 to 15 million per ml or whatever twice , which i hope was true but still needs to be higher anyway.

Really hoping this works. Not sure what the odds are. My sperm was normal before trt.

Anyhoo, I said clomid but i meant enclomiphene. I always so clomid by accident. Im in Wichita and theres one fertility doctor within 100 miles. I saw him for trt, he said he would call me in clomid in a few months when i wanted to start then he retired, lol. So I went back to my teledoc, who prescribed 50 mg enclomiphene every other day.

5 weeks 4 days since last TRT dose. a little concerned my balls dont seem bigger at all. for the first time in my life i dont have a high sex drive. im fine with erections and once things get started, but not much interest outside of that. even before trt at 200 total T had very high sex drive. combination of injury, taking a break from my normal crossfit routine to work on my olympic lifting weekness, and now this.....has me absolutely deflated, lol. i lost a little weight but it looks like its all muscle. feels like no drive at crossfit and like i want to quit. im getting smoked by people i normally beat. lacking vigor.

anyway. none of that is important. i feel sore. and at first i was hit with 3 days of HORRID SORROW and depression and racing thoughts of regrets. then i got hit with a couple half days. now on the weekends like today i seem to get hit with a few hours of sadness. its really freaking weird. and im also tired.
let me sum this up. for those experienced with this sort of thing, you have no idea how much it would mean to get some responses

oh i must add i was on about 2500 iu a week of hcg that i continued roughly 3 weeks into stopping so thats about 3 weeks ago. i dont know if that kept me shut down any longer or how the heck it works with hcg. ive read different things.

does this usually work for fertility if there are no other issues?

when typically does one start to improve with regards to energy and depression?

when would i notice my testicles begin to grow?

some people have suggested that 50 mg of enclo eod or 25 a day CAN BE potent, and i could easily do with half the dose. i have no idea if this is true, but could cutting the dose in half be something i could call my doctor that may help me actually feel better or is this off base?
 

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This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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