Ipamorelin CJC Receptors and Dosing

[Pipster]

Hi all,

I've been taking ipamorelin and cjc w/o DAC for a few months now and had really good results with energy and body comp. I've read that the pulse affect can last for several days so I only take 4 days a week at 1ooiu twice a day.

My first question: do you need to cycle off for the sake of your receptors and can/should you use something like MK677 for awhile before going back on?

Second question: am I correct that 4 days a week is sufficient if using 2x daily?
The stuff is VERY pricey although I recently found a source through a good friend (pro athlete) who lived in China and worked with a Chinese Pharmacy there. He still uses them and the pricing is a fraction of what I pay through my doctor so perhaps price pain won't be an issue in the future.

 

[Cataceous]

If the effect on receptors is an issue then it is MK-677 that should be avoided. From Wikipedia: "According to some recent research and discussion, there is a concern that its particularly longer half-life might over-stimulate the ghrelin receptors in the brain."

I take ipamorelin nightly. The effects on IGF-1 have been variable, but it has remained consistently good for sleep. I recently tested a night without it, and sure enough I woke early. Back on it the next night and all was well. By this measure, at least, there was no reduced efficacy due to habituation.