I take TRT, Still Impotent Most of the Time .. Extreme Problem.. Anything Else To Check?

audiognostic

New Member
Current Regimen:

Daily propionate IM injection 9mg/day
50 mg prengenolone /day

TEST RESULT — RANGE
Hormonal
Testosterone total 733 — 350 - 1000
testosterone free 21.9 — 9.3-26.5
SHBG 22 — 10.0-57.0
Estradiol sensitive 37— 8.0-35.0
DHEA S 254.1 —138.5 - 475.2
Progesterone 0.4 — 0.0-0.5
Prolactin 8.1 — 4-15.2
DHT 50 — 30-85
Other
Free T3 (thyroid) 4 Normal 2-4.4
TSH 2.17 Normal 0.45-0.4500
A1C (diabetes) 5.2 Normal 4.8-5.6
Total cholesterol 127 LOW <200

END RESULT: 85% of the time im basically completely impotent … cant have sex… no relationships… almost never get morning wood, numb dick
anything else i need to look into?

HAVE TRIED:
AI: Doesnt do anything good for me
HCG: Seems to only make things worse
Cypionate: Seems to only make things worse
Viagra/ Cialis: Cialis does nothing, viagra helps at 100 mg but not enough

I need maybe some real deeper insight…If anyone could help offer any insight or maybe what else to check that would be greatly appreciated
 
Last edited:
Prop dose is too low I'd like to see your FT come up to the lab range max value in the trough, so 10-11mg/D of Prop.
Too your Estrogen is too high, your SHBG is on the lower side of the scale and I think that your Sensitive E should mirror that number.
I would ditch the Pregnenolone you don't need that.

Specifically what is this problem, how much and how often did you take an AI with this current therapy protocol:
AI: Doesnt do anything good for me
 
I do concur with Vince on using the NO stack in his linked thread but I think the more important part is that you've got some real tweaks to make in your protocol.
 
I’d agree, TT & FT could be higher and with your lowish SHBG your e2 is higher than you can probably handle without sides. You said AI didn’t work for you, what did you try?
 
I have low T problems which I am treating now using HCG, before it I tried to decrease my estradiol and every time I reach around 15pg I see an increase in my libido.
Sr rand McClain (check you tube) says he always keep his patients in the range of 15 to 20 using AI.

I am saying this cuz your estradiol looks high
 
My DHEA was about the same, and Defy called it low. Another thing you could try is the T gel on the scrotum to boost DHT.

Checked cortisol or growth hormone? There was one thread on this forum that claimed growth hormone was needed to make his TRT effective.
 
I have low T problems which I am treating now using HCG, before it I tried to decrease my estradiol and every time I reach around 15pg I see an increase in my libido.
Sr rand McClain (check you tube) says he always keep his patients in the range of 15 to 20 using AI.

I am saying this cuz your estradiol looks high
Recommending someone keep there e2 below 20 isn’t very safe. E2<20 has been shown to result in bone loss.
 
Recommending someone keep there e2 below 20 isn’t very safe. E2<20 has been shown to result in bone loss.
But I have been below 20pg all my life :/ that’s weird I have test that goes back 8 years ago. Also I noticed every time I reach 15 (before I started hcg) libido increase like crazy I did this three times backed up with blood test
 
your hormonal environment is unbalanced. Normal testosterone, but estrogen is slightly over range. This does not happen in healthy natural males.

I agree with getting your e2 lower but you need to find a way to accomplish it without an AI.
drop pregnenolone. use DIM and Calcium D-Glucarate.

What is your age? height? weight? do you have any other health issues?
 

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TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

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Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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