Huberman Podcast - Use TRT with Prolactin mitigation, stopping AIs, and Importance of Estrogen and the Brain

I am on that dose for 4weeks. It droped from middle to lower end of ref. range.. now My prolactin is 159 mlU/l..
it is hard to feel any sides because I started new trt protocol and go slowly up with my test dose..
 
I am on that dose for 4weeks. It droped from middle to lower end of ref. range.. now My prolactin is 159 mlU/l..
it is hard to feel any sides because I started new trt protocol and go slowly up with my test dose..
Hey what time do u take the 100mg of P5P? Do u take it on an empty stomach or with food? I’ve recently read that some people are taking it before bed because it may help with sleep, but I’ve also seen a few people say it messed with their sleep, so not sure what to make of it all
 
Hey what time do u take the 100mg of P5P? Do u take it on an empty stomach or with food? I’ve recently read that some people are taking it before bed because it may help with sleep, but I’ve also seen a few people say it messed with their sleep, so not sure what to make of it all
Just with other mornings vitamins
 
I have been saying this for years, but hardly anyone reads or listens. I am glad he is talking about how important the aromatization of testosterone to estradiol is for the brain.




 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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