How to Use HCG and Anastrozole to Preserve Fertility on Testosterone

billyjr

Member
So just a quick intro, im 31, been on trt for 3 months, had a crazy time starting. My urologist was giving me 400 mg of Test E once every 3 weeks. It was a disaster, my estrogen went crazy. So my GC prescribed me 1mg anastrozole every 3 days and to check blood work in 3-4 weeks. My last T shot was 5/6/16. Also went to a "TRT" specialist who scared the crap out of me because he said I should get my sperm frozen just incase TRT makes me infertile. So just paid for a semen analysis ($275) and should have results this week.

I am getting married soon and would love to have kids. So im not sure TRT is the way for me to go right now, maybe I should wait to have kids than go back on TRT. Either way doctor was going to try and prescribe me HCG (he said insurance companies always give him a tough time on getting it approved).

Now, lets say the semem analysis comes back and im fine, should i just blow off the whole scary thought of being infertile from TRT tx, and just continue. Because im not going to lie, i felt like a million bucks, both physically and mentally on TRT. I feel I've found a doctor who knows what hes doing, 200 cyp 1x a week, with anastrozole if my nipples flare up (did previously, obv that was 400 Test, which was crazy). I just don't want to risk in the RARE chance that I become infertile, that would be an absolute physical and emotional killer.

The place im doing the semem analysis takes no insurance, because they say the work they do rarely gets covered. To freeze the semem its $1000 first time, and $515 yearly charge after that, which I am considering doing to just be on the safe side. What are your guys thoughts?
 
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Before you spend all that money why not add HCG to your protocol, wait 6 weeks and do a fertility analysis. You can get HCG from Defy Medical no problem, although they do not take insurance. Its fair to say that TRT WITHOUT HCG is going to make you infertile (while you stay on that protocol anyway), so my 2-cents would be to add HCG to your protocol ASAP.
 
Since you're on TRT already, refine your protocol. Hopefully your doctor will let you inject very 3 1/2 days. I inject T and HCG on the same day and need no AI.
 
Billyjr

Just print these two studies and review them with your doctor.

https://www.excelmale.com/forum/showthread.php?425-Two-Studies-That-Used-HCG-with-Testosterone

This is what I do:

https://www.excelmale.com/?s=149-Ho...o-Preserve-Fertility-Libido-and-Testicle-Size

Note: I am not looking to be fertile. That is why I only inject HCG twice per week with TRT. If I was interested in fertility, I would follow Lipshultz' protocol with HCG 500 IU every other day plus TRT. It is always good to test your sperm and baseline and at week 8.
By the way, we have had one report on ExcelMale.com from a guy who was on HCG 500 IU twice per week plus 75 mg T twice per week and he had to increase his HCG frequency to three times per week to get his sperm quality to a healthy level.

You can a cheaper basic sperm analysis here: http://www.discountedlabs.com/semen-analysis/
 
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hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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