How to tell if E2 is getting high without access to sensitive test?

Hi Guys,

I started TRT about three weeks ago. I'm based in the UK so don't have access to the Sensitive E2 test. In the first week I noticed the "brain fog" lifted somewhat and I felt far more alert and able to focus better that before I started. I have noticed in the last week or so that brain fog feeling has returned. My body fat is quite high, at least 25%. I know three weeks in is still early but would it be possible for my E2 levels to have crept up in that time and be the cause of the brain fog returning?

Other symptoms I'm noticing are very slight sensitivity in one of my nipples. Erections went from poor before I started to awesome in the first two weeks and are now average. I've also noticed penis sensitivity is down to the same as I experienced pre TRT.

I have anastrozole but haven't used it since I tried HCG mono (which had no effect no me) before going onto TRT. I'm wondering if it would be worth taking 0.25mg EOD for a week to see if it helps?

It's really frustrating not to have access to the right test. What do you guys think?

More detail on my current protocol here here: Started TRT today - Protocol and Dose. Updated with Labs 20/09/18

There is no way to know unless you get an estradiol sensitive test. All symptoms can be caused by something else.
 
Hi Guys,

I started TRT about three weeks ago. I'm based in the UK so don't have access to the Sensitive E2 test. In the first week I noticed the "brain fog" lifted somewhat and I felt far more alert and able to focus better that before I started. I have noticed in the last week or so that brain fog feeling has returned. My body fat is quite high, at least 25%. I know three weeks in is still early but would it be possible for my E2 levels to have crept up in that time and be the cause of the brain fog returning?

Other symptoms I'm noticing are very slight sensitivity in one of my nipples. Erections went from poor before I started to awesome in the first two weeks and are now average. I've also noticed penis sensitivity is down to the same as I experienced pre TRT.

I have anastrozole but haven't used it since I tried HCG mono (which had no effect no me) before going onto TRT. I'm wondering if it would be worth taking 0.25mg EOD for a week to see if it helps?

It's really frustrating not to have access to the right test. What do you guys think?

More detail on my current protocol here here: Started TRT today - Protocol and Dose. Updated with Labs 20/09/18

Here is a place in the UK you can get a sensitive E2 test at:

Estrogen sensitive tests in UK??
 

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TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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