How Oral Pills Testosterone (TRT) Work, Link to TRT & Prostate Cancer

madman

Super Moderator

In this episode, Dr. Geo sits down with renowned urologist and men’s health expert Dr. Mohit Khera—professor at Baylor College of Medicine with over 160 peer-reviewed publications—to unpack the facts, myths, and future of testosterone treatment. They cover oral options, including Kyzatrex, how to interpret labs like SHBG and estradiol, and why testosterone could actually be protective—not harmful—for prostate health.This episode is packed with clarity, not hype. If you or someone you love is navigating testosterone therapy or prostate cancer recovery, this is essential listening.




Chapters


00:00 – testosterone therapy and prostate cancer – 154
03:00 – The 4 C’s of choosing a TRT treatment
04:50Oral testosterone: Kyzatrex, Tlando, and Jatenzo
06:30 – Benefits and risks of oral testosterone
09:00 – TRT and fertility: what you need to know
12:00 – Understanding free testosterone, SHBG, and labs
15:00 – Does TRT cause prostate cancer?
18:00 – New science: BAT therapy and advanced prostate cance
r22:00 – Can TRT be used after prostate cancer treatment?
26:00 – Interpreting PSA levels on testosterone
30:00 – The TRAVERSE trial and heart health
34:00 – TRT and BPH: risk or relief?
38:00 – Hormone balance: estrogen, DHT, and more
44:00 – Key takeaways: personalized care, not one-size-fits-all
47:00 – How to get tested and talk to your doctor
50:00 – Final thoughts from Dr. Khera & Dr. Geo




If you’re exploring TRT, dealing with prostate cancer recovery, or just want to age better, this is an episode you can’t afford to miss.
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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