How do you know when to take an AI.

firefighterinNC

New Member
Still working with a urologist to get dialed in.

My complaints about lack of libido and sensitivity downstairs are still my biggest issues. Energy and sleep quality seemed to be getting better. I was actually saying to myself I felt pretty good lately and at times for 1-2 days infrequently I think libido is getting better, but it's gone just a quick.

My urologist recently upped my dose to 150 mg of test cyp split into two doses weekly, he did mention he has folks take test cypionate eod and they have good success. My sensitive e2 came back in the at 52 and my testosterone was 1128. He suggested checking prolactin which was 9.7 ng/ml, so that was normal.
He also gave me aromatase inhibitor anastrozole and told me to take a quarter. I don't like that the way that makes me feel at all, depressed and irritable. The previous urologist prescribed aromasin and I did not have that depressed irritable feeling when I took it.
The current urologist just didn't have many answers for me. He said I might not be on high enough dose to get my levels to where they need to be. He said some folks sometimes need an ester change and some folks have to get estrogen under control. He said mine was elevated but not bad ( whatever that means). He wanted me to give it 8 weeks and re evaluate.

His response was to take the AI as needed.
I guess i'm dumbfounded here, when and how do I know when this would be needed? I just had a follow up with my pcp and I told her I felt like the increasing of the dose was the wrong way to go but she told me to just stay the course and see how it went at the 8 week follow up. I'm on week 3 of this dose increase and I can feel this inner anxiety creeping up this week that I didn't have the previous two weeks. Financially I don't have the means to get independent labs so i'm trying to work with my pcp and my urologist.
One thing i have noticed is that towards the end of my week if I miss an injection day or go past an injection date my libido increases. That makes me think i'm on to high of a dose, but what do I know.
Regards,
 

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⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

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Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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