Hot Flashes when E2 is low??

[Gianluca Bonetti]

Hi Guys, unfortunately my TRT hasn't been going well for several months now and really trying to figure things out with the Doc, so I had my last conversation with Doc Dr John Crisler not long time a go, my E2 levels on June was 27 pg/mL on a scale 8 to 35, last blood work LabCorp tested for "Estradiol Roche ECLIA methodology" so Doc said basically that is wrong way on testing and we don't have a number, from June I decreased my anastrazole from 0.12 twicwe a week to 0.1 a week, I believe, not sure how much actually the level went up but I personally don't believe too much cause when I wasn't using any anastrazole my E2 was up t0 52 on 200mg a week of T and 350IU 3 x week of HCG

so here is the fact, I'm having hot flashes, sweet at night water retention all symptoms of high E2, so doc said to treat symptoms and not numbers, totally make sense, but funny it is that when my E2 was up to 52pg/mL I had no water retention, or hot flashes so is having a normal E2 levels giving me all this??
also water retention equal high blood pressure correct?? I now do 3 injections of 0,35ml subq and take 3 times 0.1/200mg of anastrazole 3 times a week lets see

 

[Vince Carter]

Low E can share symptoms of high E...you might consider the Anastrozole @ .1mg twice per week and see how that feels.

 

[CoastWatcher]

Water retention during TRT is not necessarily tied to high blood pressure. It's always a good idea, however, to monitor blood pressure on a regular basis.

 

[Gianluca Bonetti]

that is interesting, do you believe that going months with high e2 like I did around 52 could be fine and feeling ok until a point when your body start showing all symptoms even though I started treat high E2 and numbers went down? like I would need now months of low E2 number to get rid of water and other related side effect or if number are low I should get rid of symptoms almost instantly?

 

[lcvl]

Are you sure you need that much T every week? Maybe lowering your dose might help. I personally think you're still at high E.
I've been at high E both with and (almost) without symptoms, depending on how long I was on a specific protocol. Sometimes it takes time for the symptoms to appear.

 

[Gianluca Bonetti]

yes with 200mg a week mt total was about 800 and not feeling good at all, just switched with about 65mg 3 x week subQ,

 

[GeauxBears]

Seems like you have a lot of changes going on. It would be great to see bloodwork in a few weeks after whatever protocol you are on stabilizes a bit.

In my anecdotal experience, hot flashes and sweating are more symptomatic of low E2 than high (again, for me). I also experience water retention on higher dosages of T, regardless of how controlled my E2 is. I solved the water retention issue by reducing my T a bit.

 

[Gianluca Bonetti]

that could probably be it, I should be waiting another 2/3 weeks to see levels, although I think I'll go ahead and switch back to IM injections cause SubQ make me feel even worse