1 week into treatment. Night sweats and extreme thirst. Cant sleep.

Just thought I'd make a quick update since I said I would. You guys were on the ball when you said I crashed my E2. After writing the original post I stopped taking the anastrazole and starting the next night I started to feel symptom relief. 2 days after I stopped getting hot flashes and execcive thirst entirely and was able to sleep normally.

I'm still taking the t shots and feeling pretty great from it, more energy and better mood and libido!

Thanks again to everyone who answered! Cheers.

I'm delighted to learn that the elimination of the AI has you improving. You learned an uncomfortable but important lesson, one that most of had to learn - we must take charge of our health. It's up to each one of us, not our doctors, to manage our healthcare, particularly our TRT protocols, so as to achieve optimal results. This may not be the last time you'll discover a doctor doesn't understand all the elements of androgen replacement.

All the best!
 

hCG Mixing Calculator

HCG Mixing Protocol Calculator

TRT Hormone Predictor Widget

TRT Hormone Predictor

Predict estradiol, DHT, and free testosterone levels based on total testosterone

⚠️ Medical Disclaimer

This tool provides predictions based on statistical models and should NOT replace professional medical advice. Always consult with your healthcare provider before making any changes to your TRT protocol.

ℹ️ Input Parameters

Normal range: 300-1000 ng/dL

Predicted Hormone Levels

Enter your total testosterone value to see predictions

Results will appear here after calculation

Understanding Your Hormones

Estradiol (E2)

A form of estrogen produced from testosterone. Important for bone health, mood, and libido. Too high can cause side effects; too low can affect well-being.

DHT

Dihydrotestosterone is a potent androgen derived from testosterone. Affects hair growth, prostate health, and masculinization effects.

Free Testosterone

The biologically active form of testosterone not bound to proteins. Directly available for cellular uptake and biological effects.

Scientific Reference

Lakshman KM, Kaplan B, Travison TG, Basaria S, Knapp PE, Singh AB, LaValley MP, Mazer NA, Bhasin S. The effects of injected testosterone dose and age on the conversion of testosterone to estradiol and dihydrotestosterone in young and older men. J Clin Endocrinol Metab. 2010 Aug;95(8):3955-64.

DOI: 10.1210/jc.2010-0102 | PMID: 20534765 | PMCID: PMC2913038

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