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Defy Medical TRT clinic doctor
Beyond Testosterone Book by Nelson Vergel
Study shows patients have a positive perception of testosterone nasal gel


Urologists and patients may have preconceived notions when it comes to acceptance and usability of various replacement testosterone therapies (TTh). We make assumptions that men will prefer a needle over a patch or a topical gel over a nasal gel. When Natesto® testosterone nasal gel (TNG) was introduced in Canada, we all weren’t too sure how it would be accepted. We presumed that nasal administration and twice daily (bid) to three times daily (tid) dosing would either be a big deal, leading to resistance by patients or no big deal, leading to widespread adoption. The truth is, beyond anecdote, we haven’t really examined patient preference of TNG vs. topical TTh. The My-T study in this month’s issue of CUAJ sheds some light on this subject in both novice and experienced users of replacement TTh.








What is interesting in this study is that patients, the majority of whom were prior testosterone users (experienced), perceived TNG to be more effective and convenient despite the more frequent dosing schedule than the available alternatives. Patient compliance to treatment is an issue that plagues clinical care. The concern that bid or tid dosing will lead to patient dissatisfaction was not demonstrated in this study. In fact, this study sheds positive light on TNG from the practical viewpoint of the patient. It would be interesting to see if this translates into a change in prescribing patterns by both urologists and primary care providers at large.
 

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